Results 81 to 90 of about 2,651,920 (362)

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Assessing the effects of technological progress on energy efficiency in the construction industry: A case of China [PDF]

open access: yes, 2019
Energy-saving technologies in buildings have received great attention from energy efficiency researchers in the construction sector. Traditional research tends to focus on the energy used during building operation and in construction materials production,
Feng, W, Li, J, Li, X, Zhang, Z, Zhu, W
core  

A New Theoretical and Technological System of Imprecise-Information Processing [PDF]

open access: yesarXiv, 2016
Imprecise-information processing will play an indispensable role in intelligent systems, especially in the anthropomorphic intelligent systems (as intelligent robots). A new theoretical and technological system of imprecise-information processing has been founded in Principles of Imprecise-Information Processing: A New Theoretical and Technological ...
arxiv  

Cyclical phenomena in technological change [PDF]

open access: yesarXiv, 2020
The process of technological change can be regarded as a non-deterministic system governed by factors of a cumulative nature that generate cyclical phenomena. In this context, the process of growth and decline of technology can be systematically analyzed to design best practices for technology management of firms and innovation policy of nations.
arxiv  

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Technology as Cultural Process [PDF]

open access: yes, 1988
Amongst the various approaches to analysing people’s attitudes to risks, technologies and their managing institutions, which have developed such a rich texture in recent years, one can see two fundamentally different metaphysics from one or the other of which nearly all approaches originate.
openaire   +3 more sources

A Comparative Frequency Analysis of Maximum Daily Rainfall for a SE Asian Region under Current and Future Climate Conditions

open access: yesAdvances in Meteorology, 2017
The impact of changing climate on the frequency of daily rainfall extremes in Jakarta, Indonesia, is analysed and quantified. The study used three different models to assess the changes in rainfall characteristics.
Velautham Daksiya   +2 more
doaj   +1 more source

Novel high contrast grating hollow core waveguides for enhanced gas spectroscopy [PDF]

open access: yesEPJ Web of Conferences
The article presents an innovative approach to confining waves in planar high contrast grating hollow core waveguides, design achieves a surface that reflects waves effectively while maintaining a structure that allows for high transmission.
Thottoli Ajmal   +4 more
doaj   +1 more source

The Tech Decoupling [PDF]

open access: yesarXiv, 2023
Financial market volatility is a crucial factor for investment planning, option pricing, and financial market regulation, and technology is widely recognized as a key driver of economic growth. In this project, we investigate the co-movement of technology and non-technology sectors over the last two decades.
arxiv  

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