Results 41 to 50 of about 245,064 (314)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Effect of a technological program for motor educational on the development of fundamental motor skills and some Emotional, social variables for the pre-school [PDF]
Assiut Journal of Sport Science and Arts, 2018 The study aimed to design a proposed program for motor education using multimedia (a technological program for motor educational) and monitor its effects on the development of fundamental motor skills and some emotional, social variables for the pre ...
Rehab Adel Gabal
doaj +3 more sources
A TECHNOLOGY FOR PROGRAM MAINTENANCE: PROGRAMMING KEY RESEARCHER BEHAVIORS IN A STUDENT HOUSING COOPERATIVE [PDF]
Journal of Applied Behavior Analysis, 1991 Behavioral researchers play critical, but often unanalyzed, roles in the programs they develop. Unless they replace their key activities with standardized procedures, their continued participation may be essential to program success—a situation that is often not only impractical but may be prohibitively expensive and disliked by local staff. This study
D E, Altus, T M, Welsh, L K, Miller
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
CGIAR Research Program on Policies, Institutions, and Markets: Priorities for 2019–2021
, 2021 The CGIAR Research Program on Policies, Institutions, and Markets (PIM) works with research and implementation partners in Africa, Asia, and Latin America to generate evidence, develop capacity, and support policies that help poor people, both men and ...
CGIAR Research Program on Policies, Institutions, and Markets (PIM)
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
INFORMATION FLOW THROUGH JADC2 AND THE NAVY TACTICAL GRID IN AN AUSTERE MARITIME ENVIRONMENT
, 2023 Student Thesis (NPS NRP Project Related)As articulated by the National Defense Strategy (NDS) and National Security Strategies (NSS), potential adversaries have been developing sophisticated technological capabilities. Capabilities such as anti-area/area
Locke, Erik J., Prettyman, Austin D.
core
Endogenizing Technological Change: Matching Empirical Evidence to Modeling Needs [PDF]
Given that technologies to significantly reduce fossil fuel emissions are currently unavailable or only available at high cost, technological change will be a key component of any long-term strategy to reduce greenhouse gas emissions.
William A. Pizer, David Popp
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source