Results 51 to 60 of about 1,322,340 (315)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Geothermal Reservoir Technology Research Program: Abstracts of selected research projects [PDF]

open access: yes, 1993
Research projects are described in the following areas: geothermal exploration, mapping reservoir properties and reservoir monitoring, and well testing, simulation, and predicting reservoir performance. The objectives, technical approach, and project status of each project are presented.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Decentralized Solar Energy Technology Assessment Program: Research Plan. [PDF]

open access: yes, 1979
The Decentralized Solar Energy Technology Assessment Program (TAP) is a program sponsored by the Office of Solar, Geothermal, Electric and Storage Systems, Department of Energy (DOE). The major purpose of the program is to assess the social, political, institutional and life-style impacts of the widespread adoption of decentralized solar technology ...
Bronfman, Benson H.   +5 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The National University of Costa Rica Program Profiles, Dynamics and Challenges of the Costa Rican Education: A Proposal for Pedagogical Innovation and the Production of Materials and Technological Didactic Resources

open access: yesRevista Electrónica Educare, 2017
Profiles, Dynamics and Challenges of the Costa Rican Education is a program planned to be executed in a five-year period: 2014-2018. It is being executed within the framework of processes of research, teaching, university extension, and production of the
Luis Alfredo Miranda-Calderón   +2 more
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Horizon 2020 program for industry 4.0: Towards a digital model of quality [PDF]

open access: yesTehnika, 2015
Program Manufuture Vision 2020 was developed as a Strategic Research Agenda and Road Maps, as a basis for EU research within Horizon 2020. This document is a response to the challenges of global competitiveness and sustainable development, seeking to EU ...
Majstorović Vidosav D.   +4 more
doaj   +1 more source

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