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The Technology Innovation Program [PDF]
, 2008 [Excerpt] The Technology Innovation Program (TIP) at the National Institute of Standards and Technology (NIST) was established in 2007 to replace the Advanced Technology Program (ATP).
Schact, Wendy H
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Study for identification of beneficial uses of space, phase 1. Volume 1: Executive summary [PDF]
The technological effects of the Space Shuttle Program are considered in terms of the development of improved products, processes, and services aimed at benefitting the public from economic and sociological points of view. As such, an outline is provided
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Technology alternatives for the SPS [PDF]
, 1980 Emerging technologies may offer advantages over those selected for the reference design adopted for the SPS. While it is not possible to list all the technological innovations that may affect the SPS, it is feasible to develop a systematic methodology ...
Chapman, P. K., Glaser, P.
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
VaccinesBackground: Although mRNA vaccines encapsulated in lipid nanoparticles (LNPs) have demonstrated a safety profile with minimal serious adverse events in clinical trials, there is opportunity to further reduce mRNA reactogenicity.
Denis N. Kisakov +18 more
doaj +1 more source
Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
Nature Communications, 2018 Innate immunity combines intra- and intercellular signalling to develop responses that limit pathogen spread. Here the authors analyse feedback and feedforward loops connecting IRF3, NF-κB and STAT pathways, and suggest they allow coordinating cell fate ...
Maciej Czerkies +9 more
doaj +1 more source
Research and competition: Best partners [PDF]
NASA's Microgravity Science and Applications Program is directed toward research in the science and technology of processing materials under conditions of low gravity.
Shaw, J. M.
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9 steps to scale climate-smart agriculture: Lessons and experiences from the climate-smart villages in My Loi, Vietnam and Guinayangan, Philippines [PDF]
, 2019 The Climate-Smart Village approach is a CCAFS agricultural research for development (AR4D) strategy for stimulating the scaling of climate-smart agriculture. CSVs are established in Southeast Asia through the CCAFS program to serve as sites for “testing,
Gonsalves, Julian +3 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source