Results 81 to 90 of about 137,653 (268)

Charting the academic output on cyanobacterial exopolysaccharides and their industrial applications

Studia Universitatis Babeș-Bolyai. Biologia
Cyanobacterial exopolysaccharides (EPS) are diverse biopolymers with significant ecological roles and growing industrial potential due to their biocompatibility, biodegradability, and functional versatility.
Maricel BOCANEALA, Giovani M. GORON, Elena RAKOSY-TICAN   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Análise Ergonômica do Trabalho no Brasil: transferência tecnológica bem-sucedida?

Revista Brasileira de Saúde Ocupacional
Objetivo: analisar o desenvolvimento da Análise Ergonômica do Trabalho (AET) no Brasil. Métodos: considerando-se a AET como tecnologia social, foi feita análise do processo de transferência tecnológica, comparando-se as características de seu emprego e ...
José Marçal Jackson Filho, Francisco de Paula Antunes Lima   +1 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Casa View: Funes, Argentina

ARQ, 2011
El cruce entre exploraciones formales orientadas por herramientas digitales y los sistemas constructivos propios de la infraestructura agrícola de inicios del siglo XX es uno de los puntos de partida de este proyecto que, al mismo tiempo, hace un ...
Diego Arraigada, Mark Lee, Sharon Johnston   +2 more
doaj  

Technology Transfer for Development

, 1992
In some respects developing countries today have fantastic opportunities that were not open to the now-developed countries: there is a vast and growing array of technological knowledge, to which developing countries have potential access, that, with proper use, may transform them from a preindustrial state to a high-income, fast-growing sophisticated ...
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Género, leña y sostenibilidad: el caso de una comunidad de los Altos de Chiapas

Economía, Sociedad y Territorio, 2006
In this paper we analyse the strategies of use and management of firewood by the families in Pozuelos, a community of the municipality of Chamula, located in the Altos de Chiapas.
Denise Soares
doaj