Results 101 to 110 of about 4,590,745 (306)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Technology transfer and sustainable development in emerging economies [PDF]
(WP 01/03 Clave pdf) This paper aims to show how the process of diffusion of "clean technologies" confronts a variety of forces at the macro level that create systematic, technological and institutional barriers to their adoption.
JAVIER CARRILLO
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Rethinking Invention: Cognition and the Economics of Technological Creativity [PDF]
Economists have typically not devoted much attention to the act of invention. This paper attempts to redress this situation by exploring a form of cognition, analogical transfer, which is thought by some researchers to lie at the heart of successful ...
Gary B. Magee
core
Análise Ergonômica do Trabalho no Brasil: transferência tecnológica bem-sucedida?
Revista Brasileira de Saúde OcupacionalObjetivo: analisar o desenvolvimento da Análise Ergonômica do Trabalho (AET) no Brasil. Métodos: considerando-se a AET como tecnologia social, foi feita análise do processo de transferência tecnológica, comparando-se as características de seu emprego e ...
José Marçal Jackson Filho +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The role of the international patent system in the transfer of technology to West Africa : case studies : Ghana and Nigeria [PDF]
The principal aim of this thesis is to undertake a critical examination of the role of the international patent system in the transfer of technology to West Africa, particularly Ghana and Nigeria. It focuses mainly on the patent systans and technology
Yankey, George Sipa-Adjah
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
ARQ, 2011 El cruce entre exploraciones formales orientadas por herramientas digitales y los sistemas constructivos propios de la infraestructura agrícola de inicios del siglo XX es uno de los puntos de partida de este proyecto que, al mismo tiempo, hace un ...
Diego Arraigada +2 more
doaj
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source