Results 71 to 80 of about 840,777 (236)

Pharmaceutical Technology: Drug Delivery, Formulation, and Process Research

open access: yesCHIMIA, 2006
This paper describes in the introduction the actual research trends in the area of pharmaceutical technology and the impact of FDA's PAT (Process Analytical Technology) Initiative on this research field.
Hans Leuenberger
doaj   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Patent Trend in Research Centers at Cibinong Science and Technology Park Surrounding for Determining Technology Focus

open access: yesAsian Journal of Technology Management, 2017
. Focusing in a specific technology sector would be a great strategy for early developed Science and Technology Park (STP) especially in Indonesia. Each STP has its own concept considering the resources and technology supply.
Harini Yaniar, Adityo Wicaksono
doaj   +1 more source

Card games are effective tools to enhance foundation year health and safety inductions

open access: yesFEBS Open Bio, EarlyView.
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq   +4 more
wiley   +1 more source

Trust, regulatory processes and NICE decision-making: Appraising cost-effectiveness models through appraising people and systems. [PDF]

open access: yes, 2015
This article presents an ethnographic study of regulatory decision-making regarding the cost-effectiveness of expensive medicines at the National Institute for Health and Care Excellence (NICE) in England.
Abraham J   +18 more
core   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Examining the Link Between Price Regulation, Reimportation, and Pharmaceutical R&D Investment [PDF]

open access: yes
This paper examines the link between price regulation and pharmaceutical research and development (R&D) investment. I identify two mechanisms through which price regulation (or re-importation) may exert an influence on R&D: an expected-profit effect and ...
Vernon, John
core   +1 more source

Potentiometric studies on gelatin solutions and gelatin nanoparticle dispersions [PDF]

open access: yes, 2004
Gelatin is the denaturation product of the protein collagen. The denaturation can be performed by acid hydrolysis or base hydrolysis rendering A- type or B-type gelatin respectively. Gelatin molecules have a nonuniform distribution of 18 amino acids.
Blei, C.   +4 more
core  

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

The Changing Nature of Pharmaceutical R&D - Opportunities for Asia? [PDF]

open access: yes
During the 1990''s, the pharmaceutical R&D process has witnessed tremendous technological changes. The emergence of new tools like ''combinatorial chemistry'', ''high throughput screening'' and the in-creasing use of computer-aided in silico experiments ...
Mahlich ,Jörg C.   +1 more
core   +1 more source

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