Results 61 to 70 of about 424,358 (303)

Technology acquisition strategies in pharmaceutical companies through equity investment, alliance and acquisition [PDF]

open access: yes, 2002
Thesis (S.M.M.O.T.)--Massachusetts Institute of Technology, Sloan School of Management, Management of Technology Program, 2002.Includes bibliographical references (leaves 120-121).The pharmaceutical industry is now confronted with a discontinuous time ...
Muranishi, Hiroya, 1964-
core  

Patent Trend in Research Centers at Cibinong Science and Technology Park Surrounding for Determining Technology Focus

open access: yesAsian Journal of Technology Management, 2017
. Focusing in a specific technology sector would be a great strategy for early developed Science and Technology Park (STP) especially in Indonesia. Each STP has its own concept considering the resources and technology supply.
Harini Yaniar, Adityo Wicaksono
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

The Changing Nature of Pharmaceutical R&D - Opportunities for Asia? [PDF]

open access: yes
During the 1990''s, the pharmaceutical R&D process has witnessed tremendous technological changes. The emergence of new tools like ''combinatorial chemistry'', ''high throughput screening'' and the in-creasing use of computer-aided in silico experiments ...
Roediger-Schluga,Thomas   +1 more
core   +1 more source

Periodic DFT Calculations—Review of Applications in the Pharmaceutical Sciences [PDF]

open access: yes, 2020
In the introduction to this review the complex chemistry of solid-state pharmaceutical compounds is summarized. It is also explained why the density functional theory (DFT) periodic calculations became recently so popular in studying the solid APIs ...
Łukasz Szeleszczuk   +2 more
core   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

Evaluation of the Pharmaceutical Industry Investment Program [PDF]

open access: yes
With the expiry of the Pharmaceutical Industry Investment Program (PIIP) in 2004, the Commission was asked to conduct an evaluation of the program’s rationale, effectiveness and efficiency. The study commenced in August 2002.
Productivity Commission
core  

Prospects for the Use of Medical Clays (Review)

open access: yesРазработка и регистрация лекарственных средств, 2019
Introduction. The article deals with the aspects of the use of Medical Clays in Pharmaceutical Technology. A review of the traditional areas of application of Medical Clay, as well as highlighting new directions.Text. One of the main problems of domestic
A. V. Bondarev   +3 more
doaj   +1 more source

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