Results 241 to 250 of about 4,155,604 (307)

Research on Quantitative Analysis Technology for Pacific White Shrimp Density Based on Environmental DNA. [PDF]

Ecol Evol
Liang G, Wang S, Wang S, Jiang Y, Qin Y.
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Comparative effectiveness and safety of digital health delivery models for pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: a protocol for systematic review and network meta-analysis of randomised controlled trials. [PDF]

BMJ Open
Xu L, Chen X, Yang C, Feng M, Wu Y.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Effect of home-based walking exercise and education on early functional recovery after lung cancer surgery: protocol for the WalkLung multicentre randomised controlled trial. [PDF]

BMJ Open
Zhang Y, Liu X, Shi X, Feng P, Chen Y, Lei C, Zeng H, Li T, Gui P, Li M, Wang L, Zhang R, He Y, Chen Y, Chen D, Zhang Y, Liao J, Wei X, Tian B, Liu X, Li Q, Shi Q, Chen X, Dai W.   +23 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The Increasing Value of Environmental Sustainability Assessments in Healthcare Policy and Technology Evaluation. [PDF]

Appl Health Econ Health Policy
Nicholson L, Pooley N, Skeldon G, Langham S, Wright A, Embleton N.   +5 more
europepmc   +1 more source

Global Stakeholder Perspectives on Real-World Data and Evidence in Health Technology Assessment: An Exploratory Study. [PDF]

Healthcare (Basel)
Zisis K, Pavi E, Geitona M, Athanasakis K.   +3 more
europepmc   +1 more source