Results 11 to 20 of about 15,636,570 (229)

Visual Speech in Technology-Enhanced Learning [PDF]

open access: yes, 2012
This thesis investigates the use of synthetic talking heads, with lip, tongue and face movements synchronized with synthesized or natural speech, in technology-enhanced learning.
Dey, Priya
core   +6 more sources

Reflective Practice and the Element of Surprise in Technology Enhanced Learning [PDF]

open access: yes, 2022
This is a concept paper which draws attention to the element of ‘surprise’ when it comes to educators’ self-reflections and which I apply to my own experience of implementing new forms of pedagogy in relation to technology and enhanced learning.
Smith, P, Smith, Philippa
core   +1 more source

Advances in Technology Enhanced Learning [PDF]

open access: yes, 2013
‘Advances in Technology Enhanced Learning’ presents a range of research projects which aim to explore how to make engagement in learning (and teaching) more passionate.
Lefrere, Paul   +2 more
core   +5 more sources

A Higher Education Action Research Study on the Effectiveness of an ePortfolio as a Learning Tool to Promote Reflective Professional Development [PDF]

open access: yes, 2021
Within higher education, ePortfolios have been demonstrated to enhance professional development and to promote critical thinking. In this context, one higher education level nine module, namely, the Professional Development Framework Portfolio module ...
Dunne, Kate, Logue, Pauline
core   +1 more source

Technology in learning [PDF]

open access: yes
An Association for Learning Technology and Technology Enhanced Learning Research Programme response to some questions from the Department of Business Innovation and Skills, with a foreword by John Cook and Richard ...
Schmoller, Seb
core   +6 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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