Results 121 to 130 of about 397,549 (315)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Developing age-oriented design framework with technology acceptance model for smart appliances to improve technology acceptance by ageing community in Guangzhou China [PDF]
With the growing ageing community and the rapid development of smart appliances, the acceptance of smart appliances among the ageing community presents a critical challenge in the face of demographic shift and rapid technological improvement.
Jinglong, Li +2 more
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FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Exploring user acceptance of technology using social networks
, 2009 The technology acceptance model (TAM) has been widely used to study user acceptance of new computer technologies. However, it does not incorporate social structure and influence as a significant factor.
Hossain, L, de Silva, A
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
This empirical study investigates the factors influencing Nigerians’ trust and adoption of mobile banking technology; using an integrative model. Research was conducted using a questionnaire developed and distributed in Nigeria.
Ifeonu, Robert Odera
core
The Impact Of Technology Trust On The Acceptance Of Mobile Banking Technology Within Nigeria
, 2015 With advancement in the use of information technology seen as a key factor in economic development, developed countries are increasingly reviewing traditional systems, in various sectors such as education, health, transport and finance, and identifying ...
Ward, Rupert, Ifeonu, Robert Odera
core
This paper addresses public acceptance of a proposed sub-regional, hydrogen–electric, aviation service reporting initial empirical evidence from the UK HEART project.
Patrick Langdon +7 more
core +1 more source