Results 111 to 120 of about 397,549 (315)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2010 This study aims to extend a model of technology acceptance to suit in developing country’s context. The model attempts to identify relationship between social and institutional factors over behavioural intention and usage.
Abbasi, MS, Chandio, FH, Irani, Z
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USERS ACCEPTANCE ON MIXED REALITY TECHNOLOGY [PDF]
Issues in Information Systems, 2011 Research in green computing is mainly focusing on the practices of IT vendors and businesses. This paper examines the belief and behavior of IT users in green computing.
Rasimah Yusoff +4 more
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Model of Attitudes toward the Acceptance of Mobile Phone Use in Public Places [PDF]
Since the first commercial launch of cellular telecoms by NET in Tokyo Japan in 1979 and the launch of the NMT system in Denmark, Finland, Norway and Sweden in 1981, the mobile phone has undergone continual incremental innovation for changing market ...
Brenda Mak +2 more
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Is a general extended technology acceptance model for e-learning generalizable?
Knowledge Management & E-Learning: An International Journal, 2018 e-Learning acceptance has received considerable attention in the educational technology literature. In recent years, many frameworks have been proposed, modified, and applied to better understand the factors underlying students’ acceptance of e-learning.
Tenzin Doleck +2 more
doaj
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Continuing use of information technology as value co-creation : the role of contextual variety and means drivenness [PDF]
, 2012 Understanding antecedents of Information Technology (IT) use has been a core stream within Information Systems (IS) research, and it has had a steady following since the original proposal by Davis’ Technology Acceptance Model (TAM) (Davis 1989).
Ding, Yi, Guo, Lei, Ng, Irene C. L.
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Generalization and Specialization of Technology Acceptance Model
, 2012 [[abstract]]Although recent meta analyses of Technology Acceptance Model (TAM) have appeared in the literature, practitioners, students and unseasoned scholars may still encounter difficulties in applying this TAM++ knowledge to real-world technology ...
Tao, Yu-Hui
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