Results 101 to 110 of about 1,605,773 (306)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Effective Factors on Adoption Technology among Trout Fish Farms in Guilan Province

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2015
The main purpose of this study was to investigate effective factors on adopting technologies among trout fish farmers in Guilan province by Unified Theory of Acceptance and Use of Technology (UTAUT). Statistical population of this research contained of
N. Nejadrezaei; H. Khara; M.S. Allahyari email ; M. Sadeghzadeh; K. Gharra
doaj  

Strategies for Enhancing Acceptance of New Technologies by Open, Distance, and eLearning Centers in Kenya

Teacher Education through Flexible Learning in Africa
Introducing a new technology can be very exciting especially to the technology creators. However, as espoused by the Technology Acceptance Model (TAM), while the creator of a given technology may believe that the new technology is very user-friendly, it
Michael Ngala
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

ANALYSIS OF MOBILE LEARNING IMPLEMENTATION IN BINUS UNIVERSITY [PDF]

, 2012
ANALYSIS OF MOBILE LEARNING IMPLEMENTATION IN BINUS UNIVERSITY - Mobile Learning, BiNus University, BiNus University International, BINUSMAYA Mobile, BINUSMAYA, Accessbi, Technology Acceptance Model, Perceived Mobility Value, Perceived Enjoyment ...
Andi Wenas, Huibert, DHIMAS AWLIYA RASYID, H.   +1 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Evaluation Virtual Assistant Chatbot Acceptance with an Unified Technology Acceptance and Use of Technology-Based Model

Journal of Information Systems and Informatics
The virtual assistant chatbot in the MyTelkomsel application is a company's effort to achieve goals and improve business performance. Chatbot as a virtual assistant has advantages and disadvantages.
Radhiya Sabila, Arista Pratama, Eristya Maya Safitri   +2 more
doaj   +1 more source

Effect of user experience on technology acceptance: the case of foss [PDF]

, 2009
Free and open source software (FOSS) movement essentially arises like answer to the evolution occurred in the market from the software, characterized by the closing of the source code.
Bueno Ávila, Salvador, Cossío Silva, Francisco José (Coordinador), Gallego Pereira, M. Dolores   +2 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A structural model of technology acceptance

SA Journal of Industrial Psychology, 2015
Orientation: Enterprise resource systems have not always led to significant organisational enhancement and many projects in which these systems have been implemented turn out to be over budget, not on time and unsuccessful.
Etienne Erasmus, Sebastiaan Rothmann, Chrizanne van Eeden   +2 more
doaj   +1 more source