Results 81 to 90 of about 1,605,773 (306)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Factors Affecting the Acceptability of Technology in Health Care Among Older Korean Adults with Multiple Chronic Conditions: A Cross-Sectional Study Adopting the Senior Technology Acceptance Model

Clinical Interventions in Aging, 2020
Jiyeon Ha,1 Hyeyoung K Park2 1College of Nursing, Konyang University, Daejeon, South Korea; 2College of Nursing, University of Massachusetts Amherst, Amherst, MA, USACorrespondence: Hyeyoung K ParkCollege of Nursing, University of Massachusetts Amherst ...
Ha J, Park HK
doaj  

Validity of the technology acceptance model (TAM) : A sensemaking perspective [PDF]

, 2007
This study investigates whether sensemaking activities influence technology acceptance and if the strength of relationship between TAM’s constructs changes over a period of time. This study was a panel-based longitudinal study, whereby data was collected
Aafaqi, Bushra, Jantan, Muhamad, Ramayah, T.   +2 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Consumer Attitudes Regarding Information Technology Usage [PDF]

This paper intends to formulate the hypotheses for the factors that influence individuals to adopt Information Technology as a mean to conduct the traditional services.
Durmus YORUK, Khalil MD NOR, Liliana Mihaela MOGA   +2 more
core  

Analisis Technology Acceptance Model (TAM) terhadap Penerapan E-Commerce di UKM Kota Jayapura [PDF]

, 2017
Pemanfaatan sistem informasi menjadi suatu keharusan yang tidak dapat dihindari oleh setiap Perusahaan yang ingin menempatkan dirinya pada posisi paling depan dalam suatu industri. Kemampuan sistem informasi memegang peranan yang sangat penting yang kini
Prasetianingrum, S. (Septyana), Sejati, F. R. (Fajar)   +1 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The frequency and acceptance of educational technology as a learning tool among faculty members

Journal of Medical Education Development
Background & Objective: Educational technologies improve instruction and make learning easier. They have several advantages, such as encouraging active learning, raising motivation, and improving the standard of instruction. This study aimed to determine
Farnaz Shavandi, Hossein Emad Momtaz, Nastaran Moradi, Zahra Cheraghi, Masoumeh Seidi   +4 more
doaj   +1 more source

Predicting teachers' use of an educational system by intention, attitude and self-reported use [PDF]

, 2013
Acceptance studies are for organizations a means to gain insight into users’ perceptions of a (newly introduced) technology. However, the validity of an acceptance study might be limited (a) in the case where a technology can be used receptively (e.g. to
Pynoo, Bram, van Braak, Johan
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source