Results 41 to 50 of about 210,607 (311)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

USER ACCEPTANCE OF MOBILE-JKN: INSIGHTS FROM THE TECHNOLOGY ACCEPTANCE MODEL

Jurnal Administrasi Kesehatan Indonesia
Background: Technological advancements in healthcare have driven BPJS Kesehatan Indonesia to develop the Mobile JKN application to enhance accessibility, efficiency, and quality of services.
Ferina Septiani Damanik, Anna Wahyuni Widayanti, Chairun Wiedyaningsih   +2 more
doaj   +1 more source

Tipologi Financial Technology Paylater: Technology Acceptance Model (TAM)

Formosa Journal of Multidisciplinary Research, 2023
The use of paylater fintech is currently mushrooming among the public because it makes it easier for people to shop online. The typology of fintech paylaters is based on the Technology Acceptance Model (TAM) method to determine the contribution of the magnitude of the Technology Acceptance Model (TAM) aspect in explaining the use of fintech paylaters ...
null Herlina, null Destriana Widyaningrum, null Giovanny Theotista   +2 more
openaire   +1 more source

Factors influencing policyholders' acceptance of life settlements: a technology acceptance model

The Geneva Papers on Risk and Insurance - Issues and Practice, 2021
The most significant market for life settlements (LSs) is the U.S. LSs are not present in some European countries, such as Spain, and can therefore be seen as a novel and innovative financial service in those countries. This last consideration motivates this paper, which analyses the key factors, from the seller’s perspective, for the development of a ...
Jorge de Andrés-Sánchez, Laura González-Vila Puchades, Mario Arias-Oliva   +2 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Effective Factors on Adoption Technology among Trout Fish Farms in Guilan Province

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2015
The main purpose of this study was to investigate effective factors on adopting technologies among trout fish farmers in Guilan province by Unified Theory of Acceptance and Use of Technology (UTAUT). Statistical population of this research contained of
N. Nejadrezaei; H. Khara; M.S. Allahyari email ; M. Sadeghzadeh; K. Gharra
doaj  

A technology acceptance model of satellite-based hydrometeorological hazards early warning system in Indonesia: an-extended technology acceptance model

Cogent Business & Management
Purpose This study aims to develop and test a technology acceptance model for a satellite-based hydrometeorology early warning system in Indonesia.Design/methodology/approach The model was developed by extending TAM, through the inclusion of three ...
Igif Gimin Prihanto, Hendy Gunawan, Budhi Riyanto, Wiji Prasetio, Sik Sumaedi, Tri Rakhmawati, Nidya Judhi Astrini, Mahmudi   +7 more
doaj   +1 more source

A Study on the Factors Affecting the Continuous Use Intention of Chinese Health Apps: Focusing on the Extended Technology Acceptance Model [PDF]

, 2023
Yabo Dong, Mina Lee
openalex   +1 more source