Results 81 to 90 of about 210,607 (311)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Analisis Model Penerimaan Teknologi (Technology Acceptance Model) Aplikasi BPJS Online

open access: yesJEPIN (Jurnal Edukasi dan Penelitian Informatika), 2017
Model penerimaan aplikasi  BPJS Online dalam meningkatkan pelayanan terhadap pengguna jasa yaitu pihak masyarakat melakukan evaluasi manajemen pihak bpjs dengan meminta umpan balik dari masyarakat terhadap penerimaan aplikasi BPJS online.
Marini - Marini, Sarwindah - Sarwindah
doaj   +1 more source

Building Information Modeling (BIM) Technology Acceptance Analysis Using Technology Acceptance Model (TAM)

open access: yesIPTEK Journal of Proceedings Series, 2021
Felix Andrian Prihatono   +1 more
openaire   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Modeling the electronic transactions acceptance using an extended technology acceptance model

open access: yesApplied Computing and Informatics, 2011
AbstractThe outlook for e-commerce and e-government depends not only on individuals acceptance of internet technologies as viable transaction means, but also on the recognition of the Web as a reliable milieu. In light of this, a comprehensive model describing the factors that drive individuals to accept on-line transactions over the Web was developed ...
openaire   +1 more source

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