Results 71 to 80 of about 9,667 (258)
Advanced Science, EarlyView.A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang +14 more
wiley +1 more source
Advanced Science, EarlyView.Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
Acceptance Of Internet Banking In Iran: Extension of Technology Acceptance Model (TAM)
Iranian Journal of Information Processing & Management, 2009 In the past several decades, perception of usefulness and ease of use had been the most important factors in recognition of new technologies in the field of information systems.
Muhammad Ali Bagheri +2 more
doaj
Examining Information Technology Acceptance by Individual Professionals
Gadjah Mada International Journal of Business, 2005 The mixed results of information technology (IT) investment have made the investigation of user acceptance of IT increasingly challenging. A growing body of research in user acceptance of IT literature has limited focus on individual professionals as ...
Licen Indahwati Darsono
doaj +1 more source
Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
Advanced Science, EarlyView.This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang +7 more
wiley +1 more source
Light‐Driven Competitive Selection in a Protein‐Catalyzed Dissipative Peptide Replication
Angewandte Chemie, EarlyView.A structurally flexible protein catalyzes replication within a dissipative reaction network driven by UVA‐induced disulfide rearrangements. The protein accelerates templated autocatalytic cycles with replication emerging as the dominant pathway.
Éva Bartus +12 more
wiley +2 more sources
SAGE OpenIn a working environment facing increasing digitalization and the Fourth Industrial Revolution, the acceptance of new technologies remains an important factor.
Eva Gößwein, Magnus Liebherr
doaj +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Establishing gender structural invariance of Technology Acceptance Model (TAM) [PDF]
The Asia-Pacific Education Researcher, 2010 This study examined pre-service teachers' self-reported intention to use technology. Two hundred and seven-four participants completed a survey questionnaire measuring their responses to four constructs from the Technology Acceptance Model (TAM): perceived usefulness, perceived ease of use, attitude towards use, and behavioural intention to use ...
openaire +1 more source