Results 81 to 90 of about 2,989 (212)

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

Biological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu, Reza Shirazi Nia, Junjie Sun, Chrysa Filippopoulou, Daniel De Vega, Pengtao Hu, Heng Liang, Hang Yao, Chaoyue Pan, Xiaoyan Wu, Xidong Gu, Xiaohong Xie, Georgios Giamas   +12 more
wiley   +1 more source

Embracing Change in the Modern Working Environment: Exploring the Role of Trust, Experimentation, and Adaptability in the Acceptance of New Technologies

SAGE Open
In a working environment facing increasing digitalization and the Fourth Industrial Revolution, the acceptance of new technologies remains an important factor.
Eva Gößwein, Magnus Liebherr
doaj   +1 more source

Reducing Food Waste Through Sharing Platforms: Unveiling the Rebound Effect

Business Strategy and the Environment, EarlyView.
ABSTRACT Food‐sharing platforms are nowadays recognised as a powerful tool to increase food saving. However, little is known about the key determinants fostering its usage. We propose testing the psychosocial determinants of food‐sharing app usage and its impact on post consumption behaviour by combining the technology acceptance model (TAM) with the ...
Laura Michelini, Elena Rinallo, Massimiliano Scopelliti, Alessia Pisoni   +3 more
wiley   +1 more source

Strategies for Enhancing Acceptance of New Technologies by Open, Distance, and eLearning Centers in Kenya

Teacher Education through Flexible Learning in Africa
Introducing a new technology can be very exciting especially to the technology creators. However, as espoused by the Technology Acceptance Model (TAM), while the creator of a given technology may believe that the new technology is very user-friendly, it
Michael Ngala
doaj   +1 more source

Fueling Tomorrow: Scenario Planning for the Future of Gas Stations

Business Strategy and the Environment, EarlyView.
ABSTRACT Transport electrification is reshaping the service infrastructures that mediate everyday mobility, yet most electrification scenario studies remain macrolevel and offer limited insight into how incumbent forecourt (gas‐station) networks can adapt under deep uncertainty.
Joao Gabriel Rosa, Fabiano Armellini, Jean‐Marc Robert   +2 more
wiley   +1 more source

Technology Acceptance Model (TAM): Literature Review

International Journal of Accounting, Finance, Auditing, Management and Economics
Abstract In a context of widespread digital transformation, understanding the determinants of user acceptance of technologies remains a central issue in management science and information systems. Since its initial formulation by Davis (1989), the Technology Acceptance Model (TAM) has established itself as one of the most widely used theoretical ...
openaire   +3 more sources

Extending the Technology Acceptance Model to a Circular Economy Context: A Study of Hungary's REpont Deposit‐Refund System

Business Strategy and the Environment, EarlyView.
ABSTRACT The aim of the study is to examine the public acceptance of the deposit‐refund system (DRS), introduced in the European Union, through an extended version of the Technology Acceptance Model (TAM). The research supplemented the classic constructs of TAM (behavioral intension, perceived usefulness, and perceived ease of use) with environmental ...
József Ráti, Zalán Márk Maró
wiley   +1 more source

Critical Success Factors and Stakeholder Influence for Environmental, Social and Governance Assessment and Reporting

Business Strategy and the Environment, EarlyView.
ABSTRACT Environmental, Social and Governance (ESG) assessment criteria have drawn substantial attention by investors in recent years. ESG factors have been considered by investors to create greater wealth and better investment decisions and opportunities. However, there are ambiguities about ESG assessment and reporting with issues of transparency and
Caleb Boadi, Robert Osei‐kyei, Vivian W. Y. Tam   +2 more
wiley   +1 more source

The Factors Affecting Students Attitudes toward Learning via Cellular Phone: A Study on Students of Isfahan University of Medical Sciences Using Technology Acceptance Model [PDF]

Strides in Development of Medical Education, 2013
Background & Objective: Learning via mobile as a new stage of electronic learning development has been introduced to provide opportunities for transferring information and improving students learning The present study was carried out to investigate the ...
Bibi Eshrat Zamani, Bibi Eshrat Zamani, Hasan Babri, Setare Mosavi   +3 more
doaj