Results 121 to 130 of about 7,254,348 (387)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

'Look Up': The Cell Phone Manifesto

open access: yesMedia Theory, 2018
The world around us is slowly insulating itself through rapid technological advancements. At the forefront of this change is the onset of a dangerous smartphone addiction.
Sophie Beren
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cyber Hygiene as an Effective Psychological Measure in the Prevention of Cyber Addictions

open access: yesПсихология и право
Problematic internet use and addiction have grown globally with increased digital access and device usage. Individuals are spending more time online, frequently developing non-adaptive habits and addiction symptoms.
S.S. Gulyamov, A.A. Rodionov
doaj   +1 more source

Translating research findings into practice: example of treatment services for adolescents in managed care. [PDF]

open access: yes, 2006
An important question in the alcoholism treatment field is how research findings can be translated into real-world clinical practice. Researchers have developed a new research-practice integration (RPI) model that can both drive the formulation of ...
Sterling, Stacy, Weisner, Constance
core  

Development of a Coding Instrument to Assess the Quality and Content of Anti-Tobacco Video Games [PDF]

open access: yes, 2015
Previous research has shown the use of electronic video games as an effective method for increasing content knowledge about the risks of drugs and alcohol use for adolescents.
Alber, Julia M.   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Online methods of managing auditory hallucinations: A new trend to understand psychopathology

open access: yesIndian Journal of Psychological Medicine, 2017
Treatment seekers use various coping methods to reduce the distress associated with auditory hallucinations. With the increase use of technology, the technology means are also in use to manage the auditory hallucination.
Manoj Kumar Sharma, Poornima Mahindru
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Problematic technology use during adolescence: why don’t teenagers seek treatment? [PDF]

open access: yes, 2015
In recent issues of Education and Health, I have briefly reviewed the empirical evidence relating to problematic use of technology by adolescents including online video gaming (Griffiths, 2014), social networking (Griffiths, 2013a; Kuss & Griffiths, 2011)
Griffiths, MD
core  

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