Results 141 to 150 of about 8,497,329 (308)
Euphoria, Ecstacy, Inebriation, Abuse, Dependence, and Addiction: A Conceptual Analysis
, 2005 A conceptual analysis of basic notions of addictiology, i.e., Euphoria, Ecstasy, Inebriation, Abuse, Dependence, and Addiction was presented. Three different forms of dependence were distinguished: purely psychic, psycho-physiological, and purely somatic
Buhler, Karl-Ernst
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
CHILDREN'S DIGITAL LITERACY: PARENTAL ROLE IN PROTECTION AMID PANDEMIC AND DIGITAL SHIFT
InformasiThe COVID-19 pandemic has brought significant changes to family life, including the role of parents in accompanying their children in the digital era. This study examines the role of parents in supporting children's digital literacy during the pandemic ...
Rita Pranawati +2 more
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Rational Addiction to Cinema? A Dynamic Panel Analysis of European Countries. [PDF]
A number of papers have empirically investigated the rational addiction model proposed by Becker and Murphy (1988) by using data on different harmful drugs, like cigarettes, alcohol, caffeine, opium, cocaine; but also activities independent of a ...
Sisto, Andrea, Zanola, Roberto
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Wikipedia use: Risk for developing technology addiction. [PDF]
Ind Psychiatry J, 2016 Sharma MK.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Technology Addiction Survey: An Emerging Concern for Raising Awareness and Promotion of Healthy Use of Technology. [PDF]
Indian J Psychol Med, 2017 Sharma MK +4 more
europepmc +1 more source