Results 111 to 120 of about 5,896,949 (323)

Patent Information Use in Engineering Technology Design: An Analysis of Student Work.

open access: yesIssues in Science and Technology Librarianship, 2017
How might engineering technology students make use of patent information in the engineering design process? Librarians analyzed team project reports and personal reflections created by students in an undergraduate mechanical engineering technology ...
Margaret Phillips, Dave Zwicky
doaj   +1 more source

The Stability of Boats: A Science, Technology, Engineering, and Mathematics (STEM) Exercise [PDF]

open access: yes, 2015
In what might be called genuine Science, Technology, Engineering, and Mathematics (STEM), an engineering construct subject to well-understood physical principles is analyzed mathematically to yield predicted behavior.
Rublein, G.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

ENGINEERING AND TECHNOLOGY IN INDUSTRIAL CIVILIZATION CULTURE

open access: yesAdvanced Engineering Research, 2012
Both internal logic of the engineering and technolo gy development, and their sociocultural aspect is analyzed. The concepts under study are considered in connection with the existence, activity, values of the society.
Evgeny I. Sedov, Artur E. Sedov
doaj  

Engineering Workflow: The Process in Product Data Technology [PDF]

open access: yes, 2000
The prevailing paradigm for enterprises in the new decade is undoubtedly speed. This enterprise view is driven by the availability of e-business technology that enables new forms of collaboration between companies.
Bijwaard, D.J.A.   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

ENGINEERING AND TECHNOLOGY IN INDUSTRIAL CIVILIZATION CULTURE

open access: yesВестник Донского государственного технического университета, 2018
Both internal logic of the engineering and technolo gy development, and their sociocultural aspect is analyzed. The concepts under study are considered in connection with the existence, activity, values of the society.
Evgeny I. Sedov, Artur E. Sedov
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy