Results 41 to 50 of about 13,350,536 (306)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Population-based screening – the difficulty of how to do more good than harm and how to achieve it

Swiss Medical Weekly, 2010
Screening people without symptoms of disease is an attractive idea. Screening allows early detection of disease or elevated risk of disease, and has the potential for improved treatment and reduction of mortality.
M Zwahlen, N Low, B Borisch, Egger, R Obrist, F Paccaud, NM Probst-Hensch   +6 more
doaj   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Factors Affecting E-Learning Acceptance among Students of Tehran University of Medical Sciences Based on Technology Acceptance Model (TAM) [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2012
Introduction: Application of information technology in educational systems is an active program and educational process, which illustrates modern education in the third millennium.
Abasalt Khorasani, Jamal Abdolmaleki, Hossein Zahedi   +2 more
doaj  

Holistic assessment of intelligent technologies: Top management’s perceptions [PDF]

MATEC Web of Conferences, 2020
Due to the beginning of the Fourth Industrial Revolution based mainly on intelligent technologies used in the production area, rational assessment of their functioning has become the subject of interest of many scientists.
Ejsmont Krzysztof
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Transparenz normativer Orientierungen in partizipativen TA-Projekten

TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2019
In partizipativen TA-Projekten treffen Teilnehmende mit unterschiedlichen normativen Orientierungen aufeinander. Wir stellen einen methodischen Ansatz vor, der alle Beteiligten dabei unterstützen soll, mit dieser Wertepluralität offen und transparent ...
Clemens Mader, Lorenz M. Hilty, Claudia Som, Patrick Wäger   +3 more
doaj   +1 more source

Progress toward Health System Readiness for Genome-Based Testing in Canada

Current Oncology, 2023
(1) Background: Genomic medicine harbors the real potential to improve the health and healthcare journey of patients, care provider experiences, and improve the health system efficiency—even reducing healthcare costs.
Don Husereau, Eva Villalba, Vivek Muthu, Michael Mengel, Craig Ivany, Lotte Steuten, Daryl S. Spinner, Brandon Sheffield, Stephen Yip, Philip Jacobs, Terrence Sullivan, Larry Arshoff   +11 more
doaj   +1 more source

Models and applications for measuring the impact of health research: update of a systematic review for the Health Technology Assessment programme.

Health Technology Assessment, 2016
BACKGROUND This report reviews approaches and tools for measuring the impact of research programmes, building on, and extending, a 2007 review. OBJECTIVES (1) To identify the range of theoretical models and empirical approaches for measuring the impact
J. Raftery, S. Hanney, T. Greenhalgh, M. Glover, A. Blatch-Jones   +4 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source