Results 61 to 70 of about 13,591,223 (317)

Synergism in Technology Assessment [PDF]

open access: yesInternational Journal of Technology Assessment in Health Care, 1989
In 1899, Charles H. Duell, Commissioner of the U.S. Office of Patents, urged President McKinley to abolish the Patent Office by saying, “Everything that can be invented has been invented.” Fortunately for the health care industry, there have been more significant “medical inventions” in the 89 years following Duell's utterance than in all of recorded ...
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Dr. Seltsam, oder wie ich lernte, die Drohne zu lieben

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2018
Drohnen werden inzwischen in vielen und sehr unterschiedlichen Kontexten verwendet. Aus dem Blickwinkel der Technikfolgenabschätzung scheint es daher sinnvoll, den Umfang der momentanen und zukünftigen Nutzung von Drohnen und daraus resultierende ...
Karsten Weber   +2 more
doaj   +1 more source

Office of Technology Assessment (OTA) Resources, February 1995

open access: yes, 1995
This collection of Office of Technology Assessment (OTA) Resources information briefs details assessments and documents completed by OTA and categorized into a variety of topics, including the proliferation of weapons of mass destruction, defense ...
Office of Technology Assessment
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Technikfolgenabschätzung als technikwissenschaftliche Disziplin?

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2018
Aufgrund ihrer Methode wie auch Forschungspraxis kann die Technikfolgenabschätzung (TA) als eine Teildisziplin der Technikwissenschaften angesehen werden kann.
Klaus Kornwachs
doaj   +1 more source

Office of Technology Assessment List of Publications, April 1980

open access: yes, 1980
A catalog of Office of Technology Assessment (OTA) documents published through ...
Office of Technology Assessment
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Amisulpride for very late-onset schizophrenia-like psychosis: the ATLAS three-arm RCT

open access: yesHealth Technology Assessment, 2018
Background: Very late-onset (aged ≥ 60 years) schizophrenia-like psychosis (VLOSLP) occurs frequently but no placebo-controlled, randomised trials have assessed the efficacy or risks of antipsychotic treatment. Most patients are not prescribed treatment.
Robert Howard   +25 more
doaj   +1 more source

Theorie der Technikfolgenabschätzung reloaded

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2018
Vor etwa zehn Jahren identifizierte eine aufflackernde Debatte die Charakteristika Folgenorientierung, Beratungsbezug und Wissenschaftlichkeit als mögliche Eckpfeiler einer Theorie der Technikfolgenabschätzung (TA).
Stefan Böschen, Ulrich Dewald
doaj   +1 more source

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