Results 51 to 60 of about 4,522,828 (308)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Pioneering a Framework for Robust Telemedicine Technology Assessment (Telemechron Study)

open access: yesTechnologies
The field of technology assessment in telemedicine is garnering increasing attention due to the widespread adoption of this discipline and its complex and heterogeneous system characteristics, making its application complex.
Sandra Morelli   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Future Fuels—Analyses of the Future Prospects of Renewable Synthetic Fuels

open access: yesEnergies, 2019
The Future Fuels project combines research in several institutes of the German Aerospace Center (DLR) on the production and use of synthetic fuels for space, energy, transportation, and aviation.
Thomas Pregger   +25 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Methodical Comparison of Alternative Powertrain Technologies for Long-Distance Mobility Using Germany as an Example

open access: yesWorld Electric Vehicle Journal, 2019
The main barriers to the wide acceptance of electric vehicles, such as the limited driving range or the high acquisition costs, are to be countered by various technology alternatives for the powertrain of the future.
Michael Weigelt   +3 more
doaj   +1 more source

Actual metrological conditions for ionizing chamber calibration in radiotherapy [PDF]

open access: yesArchive of Oncology, 2004
BACKGROUND: Since 1976 it has been recognized that an accuracy of ±5% in the delivery of an absorbed dose to a target volume is necessary for successful therapy treatment.
Spasić-Jokić Vesna M.
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Assessment for learning in primary technology classrooms [PDF]

open access: yes, 2007
Emerging international research suggests that enhancing teacher student assessment for learning (AfL) interactions is a key to enhancing student learning.
Cowie, Bronwen   +2 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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