Results 41 to 50 of about 13,591,223 (317)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Technology Assessment in Business and Government [PDF]
, 1977 Hearings held by the Office of Technology Assessment (OTA) with the purpose of developing "a better understanding of how the processes of technology assessment have affected decisionmaking in the public and private sectors" (p.1)
United States. Congress. Office of Technology Assessment.
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The Implications of Cost-Effectiveness Analysis of Medical Technology [PDF]
, 1980 A case study by the Office of Technology Assessment (OTA) that "touches on only some of the aspects of technology assessment that might be undertaken with respect to multichannel chemistry analyzers" (p. 7)
United States. Congress. Office of Technology Assessment.
core
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Student Perceptions of Instructional Ultrasound Videos as Preparation for a Practical Assessment
Ultrasound International Open, 2019 Background Learning ultrasound early in the medical school curriculum helps students to understand anatomy and pathology and to perform defined
Martin Altersberger +5 more
doaj +1 more source
Progress toward Health System Readiness for Genome-Based Testing in Canada
Current Oncology, 2023 (1) Background: Genomic medicine harbors the real potential to improve the health and healthcare journey of patients, care provider experiences, and improve the health system efficiency—even reducing healthcare costs.
Don Husereau +11 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Health technology assessment [PDF]
International Journal of Technology Assessment in Health Care, 2009 Health technology assessment (HTA) (1), also known as healthcare technology assessment or medical technology assessment, is a form of policy research that systematically examines short- and long-term consequences of the application of a health technology, a set of related technologies, or an issue related to technology.
openaire +2 more sources