Results 61 to 70 of about 374,519 (265)

Simulation von Innovationsdynamiken im Kontext der Energiewende

TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2019
Wie können Modelle zur Simulation von Akteursverhalten bei der Politikberatung zur Entwicklung von Maßnahmen zur Unterstützung der Genese und Diffusion nachhaltiger Technologien eingesetzt werden?
Joachim Globisch, Bert Droste-Franke, Gabriele Fohr, Sandra Wassermann   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The Diffusion Model of NFC Technology in the Mobile Payment System in Iran [PDF]

Journal of Systems Thinking in Practice
This study aims to create a diffusion model for the diffusion of Near-Field Communication (NFC) technology in the mobile payment system in Iran. NFC technology is one of the technological applications that is spreading worldwide daily and being used in ...
Mehran Mohamad Madady Nia, Mohammadali Keramati, Naser Safaie, Hossein Moinzad, Seyed Abdollah Amin Mousavi   +4 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Dynamic effects of internet use on green agricultural technology adoption: evidence from five-wave panel data in rural China (2014–2022)

Frontiers in Environmental Science
IntroductionInternet access is rapidly expanding in rural China, yet its role in promoting green agricultural technology (GAT) adoption remains unclear.
Peipei Zheng, Huijun Wang
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Simulation Analysis of Artificial Intelligence Technology Diffusion under Market Competition and Policy Incentives Based on Complex Network Evolutionary Game Models

Systems
The relationship network between enterprises will change their adoption behavior of AI technology and this micro-decision-making mechanism will eventually decide whether AI technology can diffuse and the extent of diffusion on the macro level.
Xiaofei Ma, Jia Wang
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source