Results 121 to 130 of about 7,887,155 (310)
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Il disegno, il General Intellect e la città: per una rilettura del Vasari
Starting from a reinterpretation of 16th Century “teoriche” focusing on the notion of “disegno”, the article examines the use of this terms in Giorgio Vasari’s work.
Franco Farinelli
doaj
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Biophotonics: a marriage of sciences [PDF]
Biophotonics denotes a combination of biology and photonics, with photonics being the science and technology of generation, manipulation, and detection of photons, quantum units of light.
Girkin, J.M.
core
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Utilization of BIM Technology for Construction Operation Sequencing Training for General Contractors
Construction operation sequencing is vital for effectively managing construction job sites. In this regard, it is important that junior engineers learn construction operation sequencing on construction sites.
Yu-Cheng Lin, Ya-Ting Hsu
doaj +1 more source
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
How do fiscal and technology shocks affect real exchange rates? : New evidence for the United States [PDF]
Using vector autoregressions on U.S. time series relative to an aggregate of industrialized countries, this paper provides new evidence on the dynamic effects of government spending and technology shocks on the real exchange rate and the terms of trade ...
Enders, Zeno +2 more
core
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
AN EMPIRICAL STUDY OF THE RELATIVE IMPORTANCE OF SPECIFIC TECHNOLOGY SKILLS, GENERAL BUSINESS SKILLS, AND GENERAL TECHNOLOGY SKILLS [PDF]
Alan Peslak, Gary Davis
doaj

