Results 131 to 140 of about 2,779,005 (316)
Handbook of the Massachusetts Institute of Technology
, 1913 The Handbook of the Massachusetts Institute of Technology was produced by the Technology Christian Association and provided general information about MIT extra-curricular activities and area ...
Massachusetts Institute of Technology
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Development of investment securities in the United States
, 1894 Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of General Studies, 1894.by C.R.
Boss, C. R. (Charles Royce), b. 1871
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Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
How does general and specific human capital drive technology development in firms?
PLoS ONEThis paper examines the extent to which human capital within a firm is associated with technology development. We develop and apply an original and more objective measure of technological advancement based on companies' transitions from their current ...
Jihoon Shin +3 more
doaj +1 more source
Handbook of the Massachusetts Institute of Technology
, 1916 The Handbook of the Massachusetts Institute of Technology was produced by the Technology Christian Association and provided general information about MIT extra-curricular activities and area ...
Massachusetts Institute of Technology
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Technical and economic aspects of the importation of fruits from Chile
, 1924 Thesis (B.S.)-- Massachusetts Institute of Technology, Dept. of General Science, 1924 [first author], and Thesis (B.S.)--Massachusetts Institute of Technology, Dept.
Serrano Palma, Horacio, Kallet, Arthur M
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