Results 111 to 120 of about 7,887,155 (310)

Production Under Uncertainty: A Simulation Study [PDF]

open access: yes
In this article we model production technology in a state-contingent framework. Our model analyzes production under uncertainty without regard to the nature of producer risk preferences. In our model producers?
C.J. O’Donnell   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Technology based Health care an Indian perspective : opportunities and challenges [PDF]

open access: yes
Healthcare technology is in use for a decade or more in India. The use of technology in healthcare especially in public health is very common due to the recent development in Information Communication Technology.
Kannan, Srinivasan
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Knowledge Management Systems as an Interdisciplinary Communication and Personalized General-Purpose Technology [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2015
As drivers of human civilization, Knowledge Management (KM) processes have co-evolved in line with General-Purpose-Technologies (GPT), such as writing, printing, and information and communication systems. As evidenced by the recent shift from information
Ulrich Schmitt
doaj  

Foreign direct investment and spillovers : gradualism may be better [PDF]

open access: yes, 2004
In contrast to the standard literature, we show that the presence of spillovers may justify temporarily restricting the inflow of foreign direct investment. Our argument is based on two stylized features of spillovers: first, technology transfers --- and
Desmet, Klaus, Rojas, Juan A.
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Application Research and Implementation of Load Balance Technology in General Collection Platform

open access: yesDianxin kexue, 2013
With the rapid development of high-performance network technology, dynamic load balancing as an important technology in cluster system has become a cost-effective parallel/distributed computing technology focus. Through the interpretation of dynamic load
Yuan Zhang   +4 more
doaj   +2 more sources

Space Shuttle Lightning Protection [PDF]

open access: yes, 1979
The technology for lightning protection of even the most advanced spacecraft is available and can be applied through cost-effective hardware designs and design-verification techniques.
Blount, R. L.   +2 more
core   +1 more source

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