Results 61 to 70 of about 7,784,138 (308)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
General multiyear aggregation technology: Methodology and software documentation [PDF]
A general methodology is presented for estimating a stratum's at-harvest crop acreage proportion for a given crop year (target year) from the crop's estimated acreage proportion for sample segments from within the stratum. Sample segments from crop years
Baker, T. C.
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
NANOTECHNOLOGY AN EMERGING NEW TECHNOLOGY FOR INDONESIA PART I. NANOTECHNOLOGY IN GENERAL
Reaktor, 2006 Nanotechnology is shortly defined as the ability to build micro and macro material and product with atomic precistion. Feynman is considered to be the scientist who put a strong foundation for the development of nanotechnology with his phenomenal speech ...
Ratnawati Ratnawati +2 more
doaj +1 more source
Improving the management of type 2 diabetes through large-scale general practice: the role of a data-driven and technology-enabled education programme [PDF]
, 2021 Tarek Radwan +7 more
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Information Technology in General Practice: current use and views on future development
Journal of Innovation in Health Informatics, 1997 Objective: To ascertain general practitioners current use of computers and their views on future development of information technology in general practice. Design: Postal questionnaire sent to general practitioners.
Arfan Ahmed, Anita Berlin
doaj +1 more source
A feasibility study for advanced technology integration for general aviation [PDF]
An investigation was conducted to identify candidate technologies and specific developments which offer greatest promise for improving safety, fuel efficiency, performance, and utility of general aviation airplanes. Interviews were conducted with general
Hawley, K. E. +3 more
core +1 more source
Technology enhanced interaction framework
, 2013 This paper focuses on the development of a general interaction framework to help design technology to support communication between people and improve interactions between people, technology and objects, particularly in complex situations.
Angkananon, Kewalin +2 more
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source