Results 81 to 90 of about 20,845,308 (265)

Science & Technology Section General Discussion Group ALA Midwinter Conference, January 19, 2002.

Issues in Science and Technology Librarianship, 2002
This article reports on the Science and Technology Section General Discussion Group on Saturday, January 19, 2002.
Norma Kobzina
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Conceptual problems of semiotics of technology

Семиотические исследования
the article examines six fundamental questions in the philosophy of technology of an ontological, epistemological, and praxeological nature, formulated in the language of general semiotics.
Aleksandr Yu. Nesterov
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The influence of cultivation technologies on the contamination of spring wheat crops and yield in the conditions of the Nizhny Novgorod region

Аграрная наука Евро-Северо-Востока
The article presents the results of research of the influence of various cultivation technologies on the contamination of spring wheat crops and its yield for 2022–2023 in the conditions of the Nizhny Novgorod region on light gray loamy forest soil ...
A. V. Ivenin, V. V. Ivenin, Yu. A. Bogomolova, S. M. Golubev, I. I. Bugrov   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Assessment for learning in primary technology classrooms [PDF]

, 2007
Emerging international research suggests that enhancing teacher student assessment for learning (AfL) interactions is a key to enhancing student learning.
Jones, Alister, Cowie, Bronwen, Moreland, Judy   +2 more
core   +1 more source

Is a general extended technology acceptance model for e-learning generalizable?

Knowledge Management & E-Learning: An International Journal, 2018
e-Learning acceptance has received considerable attention in the educational technology literature. In recent years, many frameworks have been proposed, modified, and applied to better understand the factors underlying students’ acceptance of e-learning.
Tenzin Doleck, Paul Bazelais, David John Lemay   +2 more
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source