Results 61 to 70 of about 7,887,155 (310)

General aviation technology program [PDF]

open access: yes
The research and technology program of the civil air transportation system is reported. Research is discussed for stall/spin, crashworthiness, pilot operations, flight efficiency, propulsion, and ...

core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Technology enhanced interaction framework

open access: yes, 2013
This paper focuses on the development of a general interaction framework to help design technology to support communication between people and improve interactions between people, technology and objects, particularly in complex situations.
Angkananon, Kewalin   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

THE TECHNOLOGY OF THE INTEGRAL SCIENTIFIC ACTIVITIES

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2014
Based on complete-approach of kompletiks formulated the principle of the integrity of the technology research activities and created a general model of the complex technology of research activities, ranging from the formation of technology design and ...
Marat Makhmetovich Telemtaev   +2 more
doaj   +1 more source

North-South Diffusion of a General Purpose Technology [PDF]

open access: yes
This paper studies the effects of the diffusion of a General Purpose Technology (GPT), that spreads first within the developed country of its origin (North), and then to a developing country (South).
Alvaro Aguiar, Oscar Afonso
core  

Report on a review of selected general and application controls over the Iowa State University of Science and Technology payroll system for the period March 27 through May 11, 2007 [PDF]

open access: yes, 2008
Report on a review of selected general and application controls over the Iowa State University of Science and Technology payroll system for the period March 27 through May 11 ...

core  

Impact of topology on layer 2 switched QoS sensitive services [PDF]

open access: yes, 2010
High-bandwidth QoS sensitive services such as large scale video surveillance generally depend on provisioned capacity delivered by circuit-switched technology such as SONET/SDH.
Colle, Didier   +7 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Q & A on Customized Employment: Assistive Technology as a Workplace Support [PDF]

open access: yes, 2005
[Excerpt] Despite the promise of assistive technology, many people with significant physical disabilities remain in facility-based employment programs. Underutilization of AT to facilitate competitive employment is related to a number of critical issues.
Office of Disability Employment Policy
core   +1 more source

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