Results 61 to 70 of about 79,605 (264)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Journal of Social SciencesThe uncertainty of the rapid development of science and technology has led to ethical risks that have attracted attention from all parties. As an important guarantee for the effective development of scientific and technological innovation activities, the
YANG, Xiaofei, WANG, Zuojun, ZHANG, Zile
doaj +1 more source
Emerging models of power among South African women business leaders
SA Journal of Industrial Psychology, 2016 Orientation: This paper represents a broader study which explores how South African women business leaders construct power in their life and leadership narratives.
Lisa Kinnear, Karen Ortlepp
doaj +1 more source
Dataset about information technology governance: A survey in Colombian enterprises. [PDF]
Data Brief, 2023 Maestre-Góngora G, Aponte D.
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
How do information strategy and information technology governance influence firm performance? [PDF]
Front Psychol, 2022 Wang F, Lv J, Zhao X.
europepmc +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Social Sciences, 2018 The concept of Industry 4.0 has considerably altered the way organisations operate and has impacted every aspect of life. Furthermore, the fast-growing trend of information technology (IT) transformation in organisations and huge IT investment by ...
Farida Veerankutty +2 more
doaj +1 more source
Science and Technology in Government [PDF]
Science, 1993 R S, Nicholson, P H, Abelson
openaire +2 more sources
The financing and governance of new technologies [PDF]
, 2004 This paper examines the financial sector preconditions for the successful development of high technology sectors. It argues that there is a close relation between types of activities undertaken in different countries and their institutional structures.
openaire +3 more sources