Results 91 to 100 of about 119,282,009 (261)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Development of E-colands (Electronic Comic of Peatlands) for Junior High School Mathematics Learning

Edukasia
Low mathematical literacy among Indonesian students, as indicates by PISA results, highlights the need for innovative and contextual learning media that connect mathematics with real-life situations. This study aimed to develop and examine the feasility
Putri Sasalia S, Ramayanti Agustianingsih, Demitra Demitra   +2 more
doaj   +1 more source

Problematic Aspects of Technology Education in Slovakia

Communications, 2017
In current technology-based societies, understanding fundamental scientific concepts and theories and the ability to structure and solve scientific problems are more important than ever before.
Alena Haskova, Silvia Mandulakova, Dirk Van Merode   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

AMTEC (Association for Media and Technology in Education in Canada)

, 2005
Titre de la page Web (visionnée le 16 sept ...
Association for Media and Technology in Education in Canada
core   +1 more source

Educators’ understandings of digital classroom tools and datafication: perceptions from higher education faculty

Research in Learning Technology
Research has shown that critical data literacies development for educators is seldom a core component of most campus conversations about datafication, even as extractive, datafied systems become pervasive throughout the higher education sector.
Samantha Szcyrek, Bonnie Stewart, Erica Miklas   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Exemplary Teaching Practices in Technology & Engineering Education

, 2016
As we work to (re)define the role of K-12 technology and engineering education in general, and more specifically its role within the rainbow of STEM education, some teacher educators have struggled to identify durable and comprehensive descriptions of ...

core  

Employing structural equation modeling to discern teachers’ perspectives and their embrace of the Metaverse within the classroom setting

Frontiers in Education
The rise of smart learning environments and the transformative potential of the Metaverse are increasingly evident across various sectors, particularly in education.
Yuri V. S. Mendonça, Paola G. Vinueza-Naranjo, Diego Costa Pinto   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source