Results 41 to 50 of about 720,141 (268)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A nation's financing system is pivotal in fulfilling the demands of sustainable development. Domestic funding sources and international financial flows make substantial contributions to both economic growth and environmental quality, with their influence
Said Toumi
doaj +1 more source
Objetivou-se, com este trabalho, construir protótipos de microaspersores, com boa uniformidade de distribuição para irrigações com sobreposição em hortas agrícolas, utilizando-se os processos de prototipagem rápida e torneamento mecânico.
Alexsandro C. S. Almeida +4 more
doaj +1 more source
The relationship between firm performance feedback and technology innovation has been studied extensively, but limited attention has been paid to factors that mediate this relationship.
Li Zheng, Binbin Sun
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
This study examines factors influencing consumers’ purchase behavior of durian chips in Thailand’s digital age. A quantitative research design was employed using a sample of 350 consumers in Chanthaburi province, selected through convenience sampling ...
Chusak Chaowarot +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Shock Response Targeting Mechanism for the Poor and Vulnerable Urban Households in Nigeria
The COVID-19 pandemic has brought unprecedented hardship to the global community, with Nigeria being no exception. According to the World Bank's Poverty and Equity Brief for West Africa Nigeria (2021), more than 80 million Nigerians faced vulnerability ...
Iorwakwagh Apera +3 more
doaj +1 more source
Evaluating Green Strategies for the Reduction of Climate-Altering Gas Emissions Using LCA
According to the previsions of Paris Agreement 2015, several Green Strategies (GS) can be implemented to control and reduce the GHG emissions due to the building sector and construction industries.
Paola Marrone, Federico Orsini
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

