Results 31 to 40 of about 735,543 (263)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Co-packaged electronics with microfluidics for direct-to-package cooling

Communications Engineering
Power semiconductors operating under high heat fluxes and elevated temperatures rely on liquid-cooled heat sinks with substantial coolant volumes. Recent advancements in direct-to-chip (D2C) cooling techniques have shown enhanced thermal performance ...
Henry A. Martin, Zihan Zhang, Mahad Saeed, Sander Dorrestein, Edsger C. P. Smits, René H. Poelma, Willem D. van Driel, GuoQi Zhang   +7 more
doaj   +1 more source

Multi-UAV Bearing-Only Active Tracking via Prescribed-Shell Bearing-Geometry Self-Organization

Actuators
In multi-UAV bearing-only active tracking, the estimation and control performance is fundamentally determined by the target-centered bearing geometry, as passive angle-of-arrival measurements provide directional information without direct range ...
Hongyu Liu, Zhongjing Ren, Chao Cheng, Jianping Yuan, Mengbi Wang   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Evaluation of pest control contributions to the production of three major grain crops in China

Crop Health
Wheat, rice and maize are three major grain crops in China. In 2024, under the organization of National Agricultural Technology Extension Service Center, the contribution rates of controlling pests (diseases, insect pests and weeds) on these crops to ...
Hui Liu, Xiaoming Zhu, Fuyan Zhuo, Yue Li, Fuxiang Wang, Ping Li, Zhaoyue Ge, Yongwang Guo, Wancai Liu   +8 more
doaj   +1 more source

Integrated nano-opto-electro-mechanical sensor for spectrometry and nanometrology

Nature Communications, 2017
Fully integratable spectrometers have trade-offs between size and resolution. Here, the authors present a nano-opto-electro-mechanical system where the functionalities of transduction, actuation and detection are fully integrated, resulting in an ultra ...
Žarko Zobenica, Rob W. van der Heijden, Maurangelo Petruzzella, Francesco Pagliano, Rick Leijssen, Tian Xia, Leonardo Midolo, Michele Cotrufo, YongJin Cho, Frank W. M. van Otten, Ewold Verhagen, Andrea Fiore   +11 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A new dimension for magnetosensitive e-skins: active matrix integrated micro-origami sensor arrays

Nature Communications, 2022
State-of-the-art magnetic skins can only sense in one or two-dimensions, at small spatial resolutions. By combining the ancient art of paper folding, origami, with advanced semiconductor technology, here, authors present cutting edge three-dimensional ...
Christian Becker, Bin Bao, Dmitriy D. Karnaushenko, Vineeth Kumar Bandari, Boris Rivkin, Zhe Li, Maryam Faghih, Daniil Karnaushenko, Oliver G. Schmidt   +8 more
doaj   +1 more source