Results 51 to 60 of about 735,543 (263)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Towards Integrating Behaviour Demand Response into Simulation Based Heat Production Optimisation

Proceedings, 2018
Behaviour Demand Response (BDR) is the process of communicating with the building occupants and integrating their behavioural flexibility into the energy value chain. In this paper we will present an integrated behavioural model based on well-established
Christian Beder, Julia Blanke, Martin Klepal   +2 more
doaj   +1 more source

Numerical Simulation of an InP Photonic Integrated Cross-Connect for Deep Neural Networks on Chip

Applied Sciences, 2020
We propose a novel photonic accelerator architecture based on a broadcast-and-weight approach for a deep neural network through a photonic integrated cross-connect.
Bin Shi, Nicola Calabretta, Ripalta Stabile   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

High Performance Self-Powered Photodetectors Based on Graphene Nanoribbons/Al₂O₃/InGaZnO Heterojunctions

IEEE Photonics Journal
Self-powered photodetectors which operate without external power sources hold immense promise in future photodetection systems. To achieve high-performance self-powered optoelectronic devices, efficient electron-hole pair separation is critical to ...
Xiaoling Ye, Xiaoxiao Zheng, Lei Han, Yu Sun, Liang Wang, Ziheng Li, Wencheng Liu, Benqing Liu, Nan Han, Safia Khan, Syed Hassan Mujtaba Jafri, Mingyang Wang, Yafei Ning, Hu Li   +13 more
doaj   +1 more source

Behaviour Demand Response in District Heating—A Simulation-Based Assessment of Potential Energy Savings

Proceedings, 2019
Behaviour Demand Response (BDR) is an approach that enables the adaptation of operation of the district heating assets to dynamic market and capacity constraints by asking building occupants to participate and temporarily alter their demand profiles.
Christian Beder, Julia Blanke, Martin Klepal   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

AN INTEGRATED PERSPECTIVE ON THE ASSESSMENT OF TECHNOLOGIES: INTEGRATE-HTA

International Journal of Technology Assessment in Health Care, 2017
Objectives: Current health technology assessment (HTA) is not well equipped to assess complex technologies as insufficient attention is being paid to the diversity in patient characteristics and preferences, context, and implementation. Strategies to integrate these and several other aspects, such as ethical considerations, in a comprehensive ...
Philip, Wahlster, Louise, Brereton, Jacob, Burns, Björn, Hofmann, Kati, Mozygemba, Wija, Oortwijn, Lisa, Pfadenhauer, Stephanie, Polus, Eva, Rehfuess, Imke, Schilling, Gert Jan, van der Wilt, Ansgar, Gerhardus   +11 more
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

DEFINITION OF TECHNOLOGY AND TECHNOLOGY INTEGRATION

Use of Technology in English Language Class Technology is an effective tool for learners. Learners must use technology as a significant part of their learning process. Teachers should model the use of technology to support the curriculum so that learners can increase the true use of technology in learning their language skills.
Khalikova, Dilafruz, Yuldasheva, Gulkhayo   +1 more
openaire   +2 more sources