Results 41 to 50 of about 634,592 (314)

Analysis of the Topology and Electromagnetic Characteristics of Novel Stator Partitioned Axial Flux Disk Generator for Vehicles

open access: yesIEEE Access, 2023
Internal combustion engines emit high-temperature, high-pressure, and text high-speed exhaust gases, resulting in wasted energy and low thermal efficiency.
Lintao Li   +4 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Numerical Simulation of an InP Photonic Integrated Cross-Connect for Deep Neural Networks on Chip

open access: yesApplied Sciences, 2020
We propose a novel photonic accelerator architecture based on a broadcast-and-weight approach for a deep neural network through a photonic integrated cross-connect.
Bin Shi   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Towards Integrating Behaviour Demand Response into Simulation Based Heat Production Optimisation

open access: yesProceedings, 2018
Behaviour Demand Response (BDR) is the process of communicating with the building occupants and integrating their behavioural flexibility into the energy value chain. In this paper we will present an integrated behavioural model based on well-established
Christian Beder   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Behaviour Demand Response in District Heating—A Simulation-Based Assessment of Potential Energy Savings

open access: yesProceedings, 2019
Behaviour Demand Response (BDR) is an approach that enables the adaptation of operation of the district heating assets to dynamic market and capacity constraints by asking building occupants to participate and temporarily alter their demand profiles.
Christian Beder   +2 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

High Performance Self-Powered Photodetectors Based on Graphene Nanoribbons/Al2O3/InGaZnO Heterojunctions

open access: yesIEEE Photonics Journal
Self-powered photodetectors which operate without external power sources hold immense promise in future photodetection systems. To achieve high-performance self-powered optoelectronic devices, efficient electron-hole pair separation is critical to ...
Xiaoling Ye   +13 more
doaj   +1 more source

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