Results 61 to 70 of about 1,294,318 (267)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Prospectiva Tecnológica como base de la Innovación en una compañía colombiana de insumos para el sector construcción

open access: yesTeuken Bidikay, Revista Latinoamericana de Investigación en Organizaciones Ambiente y Sociedad, 2013
El presente artículo da a conocer el desarrollo de un estudio que tiene como objetivo proponer alternativas y herramientas para la implementación de prospectiva tecnológica en una empresa dedicada a la producción y comercialización de insumos para la ...
Erica Yaneth Guisao G.   +2 more
doaj  

Requirements for a systems-based research and development management process in transport infrastructure engineering

open access: yesSouth African Journal of Industrial Engineering, 2015
The management of research and development (R&D) in the transport infrastructure field is complex due to the multidisciplinary nature of the work. The literature shows that linear R&D models that progress from idea through to consumer product are not ...
Rust, Frederik Christoffel
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Medios de control para un sistema de gestión de la innovación en las empresas manufactureras: caso agroindustria

open access: yesIngeniería Industrial, 2015
El presente artículo constituye el primer avance de una investigación que pretende proponer una metodología de diagnóstico sobre un sistema integrado de gestión de la innovación (SIGI), mediante una investigación cuantitativa y cualitativa en las ...
Manuel-Fernando Montoya-Ramírez
doaj   +1 more source

Addressing Burnout among Healthcare Technology Management Professionals. [PDF]

open access: yesBiomed Instrum Technol, 2023
Andiappan M, Dufour L, Senkaiahliyan S.
europepmc   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Połączenie sztucznej inteligencji i tokenów NFT – nowe wyzwania dla rynku sztuki?

open access: yesStudia i Materiały
Purpose: The article aims to identify the challenges for the art market resulting from the use of generative artificial intelligence (GenAI) and in particular the interdependence between GenAI and NFT tokens. Methodology: Research methods – literature
Włodzimierz Szpringer
doaj   +1 more source

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