Results 111 to 120 of about 23,727 (257)

Effect of isoflurane and sevoflurane on TEER in vitro.

, 2013
(A) In a monoculture model bEnd.3 cells were exposed for 20 minutes to room air only (airR), airR containing 1.5% of either isoflurane or 3.5% of sevoflurane. After 24 hours TEER values were evaluated.
Clara Luh (294861), Christoph M. Zehendner (294872), Jana Hedrich (254324), Ralph Timaru-Kast (294866), Serge C. Thal (294860), Heiko J. Luhmann (294868), Eva-Verena Schaible (294863), Kristin Engelhard (294870)   +7 more
core   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Prediction of spontaneous echo contrast following mitral valve transcatheter edge-to-edge repair

International Journal of Cardiology: Heart & Vasculature
Background: Although no studies predict thrombotic events after mitral valve transcatheter edge-to-edge repair (MV-TEER), 34% of patients experience worsening spontaneous echocardiographic contrast (SEC) following MV-TEER. We hypothesized that predicting
Makoto Takeuchi, Hiroto Utsunomiya, Kiyotaka Tohgi, Ayano Hamada, Yohei Hyodo, Akane Tsuchiya, Atsuo Mogami, Hajime Takemoto, Kanako Izumi, Kosuke Takahari, Yusuke Ueda, Kiho Itakura, Hiroki Ikenaga, Yukiko Nakano   +13 more
doaj   +1 more source

Temporal profiling of M‐TEER‐related complications

Aims Transcatheter edge‐to‐edge repair of the mitral valve (M‐TEER) is known for its low complication rates. However, the optimal level and duration of post‐procedural care remain unclear.
Amin Polzin, Malte Kelm, Jean Marc Haurand, Hanna Schrameck, Fabian Voss, Patrick Horn, Jafer Haschemi, Daniel Oehler, Maximilian Spieker   +8 more
core   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
wiley   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Effects of calcium on TEER drop.

, 2015
A Effects of intra- and extracellular calcium chelation on the action of 125 nM LLO and 100 nM EqtII. For extracellular chelation 2.5 mM EDTA or EGTA was used or the medium was substituted by PBS.
Gregor Anderluh (145545), Nejc Rojko (541757), Simon Caserman (756843), Miša Mojca Cajnko (756840), Maja Marušić (756841), Matic Kisovec (756842), Mojca Benčina (540231)   +6 more
core   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

Advanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto, Emily Tsang, Marie Karen Tracy Hong Lin, Luca Mannino, Kurt V. Gothelf, Anja Boisen   +5 more
wiley   +1 more source

Comparative efficacy and safety of transcatheter edge-to-edge repair versus tricuspid valve replacement versus optimal medical therapy in moderate-to-severe tricuspid regurgitation: a network meta-analysis of randomized controlled trials

Journal of Cardiothoracic Surgery
Background Severe tricuspid regurgitation (TR) is associated with substantial morbidity and increased mortality. Transcatheter edge-to-edge repair (TEER) and transcatheter tricuspid valve replacement (TTVR) have emerged as less-invasive options for ...
Ihsan Noushad Karuppan Veettil, Anuhya Jamandlamudi, Nebeela Abdul Khader, Tea Shehu, Doris Lacej, Shivangi Jha, Obawole Mayowa, Joshua Zumba, Temirlan Ismailov, Zhanel Almaganbetova, Bertha Gabriela, Lina Hajjar, Sifat Ullah Safi, Muneeb Khawar   +13 more
doaj   +1 more source

Trans-endothelial electric resistance (TEER) measurement made across PBECs in thirteen co-culture combinations.

, 2015
The mean TEER value of monocultures (n = 35) is significantly lower ...
Annette Burkhart (779426), Torben Moos (779427), Louiza Bohn Thomsen (779425)   +2 more
core   +1 more source