Results 151 to 160 of about 23,727 (257)

Nello M. Teer

, 2009
23.5" X 31.5"/31" X 38.5"Portrait of Nello M ...
Furlow, John A.
core  

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Editorial: Case reports in structural interventional cardiology: 2024

Frontiers in Cardiovascular Medicine
Sunny Goel, Sunny Goel
doaj   +1 more source

Challenging the limits of mitral-TEER: a PASCAL case in the anatomical 'red zone': a case report. [PDF]

Eur Heart J Case Rep
Papadopoulos K, Khan LS, Tzikas A, Badescu AC, Vannan MA.   +4 more
europepmc   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

Baseline Anemia and Clinical Outcomes Following Transcatheter Edge-to-Edge Mitral Valve Repair: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Hakmi A, Alhameed A, Atasi A, Serdar O, Al-Ghabra W.   +4 more
europepmc   +1 more source

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

Mitral Transcatheter Edge-to-Edge Repair in Ventricular Functional Mitral Regurgitation and Very Severe Left Ventricular Dysfunction. [PDF]

JACC Adv
Omote K, Yamamoto M, Sugiura A, Shimura T, Kubo S, Izumi Y, Saji M, Asami M, Enta Y, Shirai S, Izumo M, Mizuno S, Watanabe Y, Amaki M, Kodama K, Otsuki H, Naganuma T, Bota H, Ohno Y, Yamawaki M, Hachinohe D, Ueno H, Nakazawa G, Otsuka T, Hayashida K, OCEAN-Mitral Investigators.   +25 more
europepmc   +1 more source

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

Advanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan, Yijie Qiu, Yan Zhu, Quan Wang, Jiangtao Lin, Yourong Duan, Qi Wang, Yi Dong   +7 more
wiley   +1 more source

Combined transcatheter mitral and tricuspid edge-to-edge repair or tricuspid edge-to-edge repair alone in moderate mitral regurgitation: a propensity-matched analysis. [PDF]

Eur Heart J
Kassar M, Praz F, Gerçek M, Fortmeier V, Kresoja KP, von Stein J, Pauschinger C, Rottbauer W, Goebel B, Denti P, Achouh P, Rassaf T, Barreiro-Perez M, Boekstegers P, Rück A, Zdanyte M, Adamo M, Vincent F, Schlegel P, Rosch S, Wild MG, Besler C, Toggweiler S, Brunner S, Grapsa J, Patterson T, Thiele H, Kister T, Tarantini G, Masiero G, De Carlo M, Sticchi A, Voss F, Polzin A, Rubbio AP, Bedogni F, Konstandin MH, Van Belle E, Metra M, Geisler T, Estévez-Loureiro R, Mahabadi A, Karam N, Maisano F, Lauten P, Kessler M, Kalbacher D, Iliadis C, Lurz P, Hausleiter J, Mahfoud F, Windecker S, Stolz L, Brugger N, Rudolph V.   +54 more
europepmc   +1 more source