Results 51 to 60 of about 21,102 (303)

Beyond Medical Therapy—An Update on Heart Failure Devices

Journal of Cardiovascular Development and Disease
Heart failure (HF) is a complex and progressive disease marked by substantial morbidity and mortality rates, frequent episodes of decompensation, and a reduced quality of life (QoL), with severe financial burden on healthcare systems.
Luigi Falco, Fabio Valente, Aldo De Falco, Raffaele Barbato, Luigi Marotta, Davide Soviero, Luigi Mauro Cantiello, Carla Contaldi, Benedetta Brescia, Enrico Coscioni, Giuseppe Pacileo, Daniele Masarone   +11 more
doaj   +1 more source

Evaluation of rapid transepithelial electrical resistance (TEER) measurement as a metric of kidney toxicity in a high-throughput microfluidic culture system

Scientific Reports, 2022
Rapid non-invasive kidney-specific readouts are essential to maximizing the potential of microfluidic tissue culture platforms for drug-induced nephrotoxicity screening. Transepithelial electrical resistance (TEER) is a well-established technique, but it
Erin M. Shaughnessey, Samuel H. Kann, Hesham Azizgolshani, Lauren D. Black, Joseph L. Charest, Else M. Vedula   +5 more
doaj   +1 more source

A Stepwise Approach for Transcatheter Edge-to-edge Repair in Very Advanced Tricuspid Regurgitation

JACC: Case Reports, 2023
Transcatheter edge-to-edge repair (TEER) is the most widely used approach for tricuspid regurgitation in patients with prohibitive surgical risk. However, TEER might not be feasible in advanced tricuspid regurgitation.
Maria Ivannikova, MD, Tanja K. Rudolph, MD, Kai Friedrichs, MD, Jan Gummert, MD, Volker Rudolph, MD, Hazem Omran, MD   +5 more
doaj   +1 more source

HDAC inhibition blocks Glyc-alb induced reduction in TEER. [PDF]

, 2016
Administration of 100 μg/mL Glyc-alb with and without TSA pretreatment (1 h) to (A) ARPE 19 cells and (B) hfRPE cells showing the resulting TEER at 6 h post treatment compared to the administration of the same concentration of Alb.
Danielle Desjardins (735474), Yueying Liu (1635625), Craig E. Crosson (769071), Zsolt Ablonczy (541113)   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Antithrombotic Therapy Following Structural Heart Disease Interventions: Current Status and Future Directions

Reviews in Cardiovascular Medicine
Interventions in structural heart disease cover many catheter-based procedures for congenital and acquired conditions including valvular diseases, septal defects, arterial or venous obstructions, and fistulas.
Andreas Mitsis, Michaela Kyriakou, Evi Christodoulou, Stefanos Sakellaropoulos, Panayiotis Avraamides   +4 more
doaj   +1 more source

Evolution of the short-term TEER in Calu-3 cell monolayers during the monolayer maturation. [PDF]

, 2016
(a) TEER measured for 20 min in the same port of the same insert on days 1–14 after the cell seeding. Red dashed lines indicate the TEER measured just before cell medium change. (b) TEER values at 20 min of the measurements in (a).
Hao Xu (6530), Hjalmar Brismar (40442), Marina Zelenina (2512255), Ying Fu (173963), Aizat Turdalieva (2512252), Hans Blom (456800), Johan Solandt (2512258), Nestan Shambetova (2512249)   +7 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Tricuspid Leaflet Gap-Reduction Maneuvers During Transcatheter Tricuspid Valve Repair

JACC: Case Reports, 2023
Transcatheter tricuspid valve edge-to-edge repair (T-TEER) has emerged as an option for treating patients with tricuspid regurgitation. Few studies have explored intraprocedural maneuvers to optimize leaflet-grasping T-TEER in order to improve technical ...
Carlos Godoy Rivas, MD, Vratika Agarwal, MD, Stephen Tomlinson, MBBS, Mark Lebehn, MD, Susheel Kodali, MD, Rebecca T. Hahn, MD   +5 more
doaj   +1 more source

TEER assay to evaluate cell differentiation and function. [PDF]

, 2018
HCEC were cultured in 5% blood derivatives (liquid and redissolved lyophilized powder forms of FBS, HPS, UltraGRO and PLTMax) and measured for TEER values on day 3.
Wei-Li Chen (548626), Lily Wei Chen (4971844), Yi-Chen Sun (3384272), Chien-Jung Huang (532887), Wen-Hui Tu (4971841), Chia-Ju Lu (3713068), Szu-Yuan Lin (791857)   +6 more
core   +1 more source