Results 51 to 60 of about 1,597,020 (256)

The leukemia-associated fusion protein MN1-TEL blocks TEL-specific recognition sequences.

open access: yesPLoS ONE, 2012
The leukemia-associated fusion protein MN1-TEL combines the transcription-activating domains of MN1 with the DNA-binding domain of the transcriptional repressor TEL.
W Martijn ter Haar   +9 more
doaj   +1 more source

The academic production on open educational resources in Portuguese/La producción académica en portugués sobre recursos educativos en abierto

open access: yesRIED: Revista Iberoamericana de Educación a Distancia, 2017
Open Educational Resources (OERs) have led to a new outlook on the circulation and production of educational content in print and digital forms. OERs have become an important element in the search for emerging and sustainable models for education ...
Airton Zancanaro, Tel Amiel
doaj   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

open access: yesAdvanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung   +7 more
wiley   +1 more source

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

open access: yesAdvanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu   +9 more
wiley   +1 more source

DDSurfer: A Weakly‐Supervised Dual‐Stream Deep Learning Framework for Cortical Surface Reconstruction From Diffusion MRI

open access: yesAdvanced Science, EarlyView.
DDSurfer reconstructs cortical surfaces directly from diffusion MRI without requiring T1‐weighted scans. By fusing complementary microstructural features and learning diffeomorphic deformations, it efficiently generates accurate white matter and pial surfaces, improving geometric fidelity and morphometric reliability across datasets for robust surface ...
Chengjin Li   +10 more
wiley   +1 more source

Determining Mobbing Perceptions and Job Satisfaction among Healthcare Professionals

open access: yesFlorence Nightingale Journal of Nursing, 2017
Aim: This study has been carried out as defi nitive to determine job satisfaction and mobbing perception of health care workers. Method: Three hundred and ninety healthcare professionals were enrolled in the study.
Nurhayat Kılıç, Havva Tel
doaj   +1 more source

Responsive Open Microfluidic Logic for Mechanical Computing

open access: yesAdvanced Science, EarlyView.
Coupling elasticity with capillarity transforms mechanical compression into binary fluidic states, enabling deterministic logic in open microfluidic circuits. This work demonstrates that computation can emerge from interactions between mechanic and fluidic domains, establishing a general strategy for embedding information processing directly within ...
Roi Almog, Bat‐El Pinchasik
wiley   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim   +12 more
wiley   +1 more source

THE PROPERTIES OF THE GROUND STATE OF THE 208Pb AND 209Bi NUCLEI USED ON THE ACCELERATOR DRIVEN SYSTEMS

open access: yesSüleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2009
: In this study, by using Hartree-Fock method with an effective nucleon-nucleon Skyrme interactions rms nuclear charge radii, rms nuclear mass radii, rms nuclear proton, neutron radii and neutron skin thickness were calculated for the natPb isotopes and ...
Eyüp TEL
doaj  

Dificultades de lectura en niños con Trastorno Específico del Lenguaje

open access: yesRevista de Investigación en Logopedia, 2019
El presente estudio examinó el rendimiento en lectura de los niños con Trastorno Específico del Lenguaje (TEL). Treinta niños con TEL y 32 niños con desarrollo normal del lenguaje, equilibrados en género, edad cronológica e inteligencia, fueron ...
Manuel Soriano-Ferrer   +2 more
doaj   +1 more source

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