Results 71 to 80 of about 1,887 (161)
Journal of Global Infectious Diseases, 2015 The worldwide epidemic of antibiotic resistance is in danger of ending the golden age of antibiotic therapy. Resistance impacts on all areas of medicine, and is making successful empirical therapy much more difficult to achieve.
Dardi Charan Kaur, Sadhana Sanjay Chate
doaj +1 more source
Cyclic Peptides for Drug Development
Angewandte Chemie, Volume 136, Issue 3, January 15, 2024.Cyclic peptides combine a number of favorable properties that make them attractive for drug development. Today, more than 40 therapeutics based on cyclic peptides are in use, and new, powerful technologies for their development suggest that this number could grow rapidly.
Xinjian Ji +2 more
wiley +1 more source
, 2010 The mass balance and pharmacokinetics of telavancin, a semisynthetic lipoglycopeptide antimicrobial agent, were characterized in an open-label, phase 1 study of six healthy male subjects.
Jonathan Cheong +3 more
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Antimicrobial Susceptibility of 6685 Organisms Isolated from Canadian Hospitals: CANWARD 2007
Canadian Journal of Infectious Diseases and Medical Microbiology, 2009 BACKGROUND: Antimicrobial resistance is a growing problem in North American hospitals as well as hospitals worldwide. OBJECTIVES: To assess the antimicrobial susceptibility patterns of commonly used agents against the 20 most common organisms isolated ...
George G Zhanel +14 more
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In vitro activity of telavancin and comparators against selected groups of Gram-positive cocci
, 2013 Telavancin is a novel, rapidly cidal, dual-action glycopeptide. This study examined its in vitro activity against relevant Gram-positive pathogens, comprising 99 meticillin-resistant Staphylococcus aureus (MRSA), 40 meticillin-susceptible S. aureus (MSSA)
Hope, Russell +3 more
core +1 more source
Telavancin activity when tested by a revised susceptibility testing method against uncommonly isolated Gram-positive pathogens responsible for documented infections in hospitals worldwide (2011–2013) [PDF]
, 2015 The broth microdilution method for telavancin susceptibility testing was revised and now utilises DMSO as solvent for stock solution preparation and diluent for stock solution dilution, following CLSI guidelines for water-insoluble agents.
Farrell, David J. +4 more
core +1 more source
, 2011 Purpose The physical compatibility of telavancin with select i.v. drugs during simulated Y-site administration was evaluated. Methods Telavancin for injection was ...
David P. Nicolau +3 more
core +1 more source
Frontiers in Microbiology, 2018 Vancomycin was bactericidal against Clostridium difficile at eightfold the minimum inhibitory concentration (MIC) using a traditional minimum bactericidal concentration (MBC) assay. However, at higher concentrations up to 64 × MIC, vancomycin displayed a
Angie M. Jarrad +5 more
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Compatibility and stability of telavancin and vancomycin in heparin or sodium citrate lock solutions
, 2012 Purpose. The compatibility and stability of telavancin and vancomycin in heparin or sodium citrate lock solutions were evaluated. Methods. Telavancin and vancomycin hydrochloride injection powder lyophilized for solution were reconstituted with 0.9 ...
Mermel, Leonard A. +2 more
core +1 more source
Telavancin (VIBATIV) for the treatment of complicated skin and skin structure infections [PDF]
, 2015 Methicillin-resistant Staphylococcus aureus has emerged as a major causative pathogen in complicated skin and skin structure infections (cSSSIs). Unfortunately, treatment failure with vancomycin has been increasingly reported.
Kanafani, Zeina A., Nawar, Tamara
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