Results 321 to 330 of about 161,718 (344)
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A survey of telomerase activity in human cancer.
European Journal of Cancer, 1997J. Shay, S. Bacchetti
semanticscholar +1 more source
Current Opinion in Genetics & Development, 1993
The ends of eukaryotic chromosomes are defined by specialized nucleoprotein complexes called telomeres. Telomeres impart stability to the genome and are of general interest due to their unique structure and unconventional mode of synthesis. Recent work has identified new components of the telomere complex and expanded our understanding of the role of ...
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The ends of eukaryotic chromosomes are defined by specialized nucleoprotein complexes called telomeres. Telomeres impart stability to the genome and are of general interest due to their unique structure and unconventional mode of synthesis. Recent work has identified new components of the telomere complex and expanded our understanding of the role of ...
openaire +2 more sources
Rinsho byori. The Japanese journal of clinical pathology, 2003
Telomerase, an intranuclear enzyme, binds to telomeres at chromosome ends, helps to elongate telomere length and is closely linked to attainment of cellular immortality, a step in carcinogenesis. Since telomerase activity has been detected in several human tumors and hematopoietic malignancies, this enzyme is thought to be a useful marker for cancer ...
Naoki, Tsuji, Naoki, Watanabe
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Telomerase, an intranuclear enzyme, binds to telomeres at chromosome ends, helps to elongate telomere length and is closely linked to attainment of cellular immortality, a step in carcinogenesis. Since telomerase activity has been detected in several human tumors and hematopoietic malignancies, this enzyme is thought to be a useful marker for cancer ...
Naoki, Tsuji, Naoki, Watanabe
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The RNA component of human telomerase
Science, 1995Jun-rui Feng +10 more
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2000
The past few years have brought a flood of new information to the telomerase field. The identification of multiple components of both the telomere and telomerase, the understanding of the importance of telomere maintenance to the long term viability of cells, and the demonstration of the utility of telomerase inhibition in limiting tumor cell growth ...
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The past few years have brought a flood of new information to the telomerase field. The identification of multiple components of both the telomere and telomerase, the understanding of the importance of telomere maintenance to the long term viability of cells, and the demonstration of the utility of telomerase inhibition in limiting tumor cell growth ...
openaire +2 more sources
The role of telomeres and telomerase in cirrhosis and liver cancer
Nature reviews: Gastroenterology & hepatology, 2019J. Nault +3 more
semanticscholar +1 more source
Dual Quantification of MicroRNAs and Telomerase in Living Cells.
Journal of the American Chemical Society, 2017Wei Ma +5 more
semanticscholar +1 more source
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
Nature, 1989C. Greider, E. Blackburn
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