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The Ruminant Telomere-to-Telomere (RT2T) Consortium

Nature Genetics
Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously 'invisible' parts of the genome and allow comparative analyses of complete genomes across entire clades. We present here an open collaborative effort, termed the 'Ruminant T2T Consortium' (RT2T), that aims to generate complete diploid assemblies ...
Kalbfleisch, Theodore, Mckay, Stephanie, Murdoch, Brenda, Adelson, David, Almansa-Villa, Diego, Becker, Gabrielle, Beckett, Linda, Benítez-Galeano, María José, Biase, Fernando, Casey, Theresa, Chuong, Edward, Clark, Emily, Clarke, Shannon, Cockett, Noelle, Couldrey, Christine, Davis, Brian, Elsik, Christine, Faraut, Thomas, Gao, Yahui, Genet, Carine, Grady, Patrick, Green, Jonathan, Green, Richard, Guan, Dailu, Hagen, Darren, Hartley, Gabrielle, Heaton, Mike, Hoyt, Savannah, Huang, Wen, Jarvis, Erich, Kalleberg, Jenna, Khatib, Hasan, Koepfi, Klaus-Peter, Koltes, James, Koren, Sergey, Kuehn, Christa, Leeb, Tosso, Leonard, Alexander, Liu, George, Low, Wai Yee, Mcconnell, Hunter, Mcrae, Kathryn, Miga, Karen, Mousel, Michelle, Neibergs, Holly, Olagunju, Temitayo, Pennell, Matt, Petry, Bruna, Pewsner, Mirjam, Phillippy, Adam, Pickett, Brandon, Pineda, Paulene, Potapova, Tamara, Rachagani, Satyanarayana, Rhie, Arang, Rijnkels, Monique, Robic, Annie, Rodriguez Osorio, Nelida, Safonova, Yana, Schettini, Gustavo, Schnabel, Robert, Sirpu Natesh, Nagabhishek, Stegemiller, Morgan, Storer, Jessica, Stothard, Paul, Stull, Caleb, Tosser-Klopp, Gwenola, Traglia, Germán, Tuggle, Christopher, van Tassell, Curtis, Watson, Corey, Weikard, Rosemarie, Wimmers, Klaus, Xie, Shangqian, Yang, Liu, Smith, Timothy, O’neill, Rachel, Rosen, Benjamin   +77 more
openaire   +3 more sources

Telomere

2015
Telomeres are specialised structures that protect chromosome ends from degradation and fusion events. In most eukaryotes, including yeast and mammals, telomeric DNA consists of short, repetitive G‐rich sequences, which end with 3′ G‐rich overhangs and are elongated by the specialised reverse transcriptase telomerase.
RAFFA, GRAZIA DANIELA, CENCI, GIOVANNI
openaire   +1 more source

Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

Nature Reviews Molecular Cell Biology, 2021
Ci Ji Lim, Thomas R Cech
exaly  

Telomere Diseases

New England Journal of Medicine, 2010
openaire   +2 more sources

Telomere regulation

Differentiation, 2018
openaire   +2 more sources

From shortening telomeres to replicative crisis

Nature Reviews Molecular Cell Biology, 2023
exaly  

Stop pulling my strings — what telomeres taught us about the DNA damage response

Nature Reviews Molecular Cell Biology, 2016
Eros Lazzerini Denchi, Agnel Sfeir
exaly  

Telomeres: protecting chromosomes against genome instability

Nature Reviews Molecular Cell Biology, 2010
Roderick J O'sullivan, Jan Karlseder
exaly  

Finding the end: recruitment of telomerase to telomeres

Nature Reviews Molecular Cell Biology, 2013
Jayakrishnan Nandakumar, Thomas R Cech
exaly  

Telomeres in cancer: tumour suppression and genome instability

Nature Reviews Molecular Cell Biology, 2017
John Maciejowski, Titia de Lange
exaly