Results 51 to 60 of about 535,757 (290)

In vivo temperature-sensitive drug release system trigged by cooling using low-melting-point microcrystalline wax

Journal of Controlled Release, 2019
Temperature-sensitive formulations are attractive controlled-release formulations, which release an incorporated drug by changes in body temperature induced by external temperature stimulation. Recently, it has been reported that wax matrix (WM) particles composed of a low-melting-point microcrystalline wax (MCW) released only a small amount of the ...
Kohei, Matsumoto, Shin-Ichiro, Kimura, Shigeru, Itai, Hiromu, Kondo, Yasunori, Iwao   +4 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Annual transient analysis of energetic, exergetic, and economic performances of solar cascade organic Rankine cycles integrated with PCM-based thermal energy storage systems

Case Studies in Thermal Engineering, 2021
In this study, the annual transient analysis of the solar cascade organic Rankine cycle integrated with the phase change material (PCM) storage and parabolic trough collectors (PTC) has been conducted.
Peyman Pourmoghadam, Mohammadsina Farighi, Fathollah Pourfayaz, Alibakhsh Kasaeian   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

points

, 2017
The CO2 compensation points for each genotype at each temperature and generation of the experiment.
Joe Hereford (2924595), Hereford, Joe
core   +1 more source

Integrating machine learning and feature analysis for predicting and managing thermal deformation in machine tools

Case Studies in Thermal Engineering
This study develops a method to predict and compensate for thermal deformation in machine tools, focusing on selecting temperature-sensitive points, establishing a predictive model, and detecting temperature anomalies.
Wen-Lin Chu
doaj   +1 more source

Effect of Defects on the Mechanical and Thermal Properties of Graphene

Nanomaterials, 2019
In this study, the mechanical and thermal properties of graphene were systematically investigated using molecular dynamic simulations. The effects of temperature, strain rate and defect on the mechanical properties, including Young’s modulus ...
Maoyuan Li, Tianzhengxiong Deng, Bing Zheng, Yun Zhang, Yonggui Liao, Huamin Zhou   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Smoothing data series by means of cubic splines: quality of approximation and introduction of a repeating spline approach [PDF]

Atmospheric Measurement Techniques, 2017
Cubic splines with equidistant spline sampling points are a common method in atmospheric science, used for the approximation of background conditions by means of filtering superimposed fluctuations from a data series.
S. Wüst, V. Wendt, V. Wendt, V. Wendt, R. Linz, R. Linz, M. Bittner, M. Bittner   +7 more
doaj   +1 more source

Simultaneously Wavelength- and Temperature-Insensitive Mid-Infrared Optical Parametric Amplification with LiGaS₂ Crystal

Applied Sciences, 2022
Ultrafast mid-infrared (mid-IR) lasers with a high pulse repetition rate are in great demand in various fields, including attosecond science and strong-field physics.
Zhixuan Hu, Jingui Ma
doaj   +1 more source