Results 1 to 10 of about 1,259,904 (287)

Biosensors for Point Mutation Detection [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Hanlin Jiang   +3 more
doaj   +3 more sources

Mutation-driven parallel evolution in emergence of ACE2-utilizing sarbecoviruses

open access: yesFrontiers in Microbiology, 2023
Mutation and recombination are two major genetic mechanisms that drive the evolution of viruses. They both exert an interplay during virus evolution, in which mutations provide a first ancestral source of genetic diversity for subsequent recombination ...
Bin Gao, Shunyi Zhu
doaj   +1 more source

Types of 23S Ribosomal RNA Point Mutations and Therapeutic Outcomes for Helicobacter pylori

open access: yesGut and Liver, 2021
Background/Aims: Point mutations in the 23S ribosomal RNA gene have been associated with Helicobacter pylori clarithromycin resistance. This study aimed to detect the prevalence of these point mutations and to investigate the role of different point ...
Sang Yoon Kim   +7 more
doaj   +1 more source

Base Editing in Peanut Using CRISPR/nCas9

open access: yesFrontiers in Genome Editing, 2022
Peanut (Arachis hypogaea L.), an allotetraploid legume of the Fabaceae family, is able to thrive in tropical and subtropical regions and is considered as a promising oil seed crop worldwide.
Anjanasree K. Neelakandan   +5 more
doaj   +1 more source

Recombinant Escherichia coli BL21 with LngA Variants from ETEC E9034A Promotes Adherence to HT-29 Cells

open access: yesPathogens, 2023
The CS21 pilus produced by enterotoxigenic Escherichia coli (ETEC) is involved in adherence to HT-29 intestinal cells. The CS21 pilus assembles proteins encoded by 14 genes clustered into the lng operon. Aim. This study aimed to determine whether E. coli
Karina Espinosa-Mazariego   +9 more
doaj   +1 more source

Target-Site Mutations and Glutathione S-Transferases Are Associated with Acequinocyl and Pyridaben Resistance in the Two-Spotted Spider Mite Tetranychus urticae (Acari: Tetranychidae)

open access: yesInsects, 2020
The two-spotted spider mite Tetranychus urticae is a difficult-to-control pest due to its short life cycle and rapid resistance development. In this study, we characterized field strains collected in 2001 and 2003 that were selected for acequinocyl ...
Jihye Choi   +5 more
doaj   +1 more source

Specific correction of pyruvate kinase deficiency-causing point mutations by CRISPR/Cas9 and single-stranded oligodeoxynucleotides

open access: yesFrontiers in Genome Editing, 2023
Pyruvate kinase deficiency (PKD) is an autosomal recessive disorder caused by mutations in the PKLR gene. PKD-erythroid cells suffer from an energy imbalance caused by a reduction of erythroid pyruvate kinase (RPK) enzyme activity. PKD is associated with
Sara Fañanas-Baquero   +16 more
doaj   +1 more source

Elastin genetic point mutation and the risk of pelvic organ prolapse

open access: yesClinical and Experimental Obstetrics & Gynecology, 2020
Aim: A missense mutation in the elastin gene (g28197A > G) is associated with an increased risk for inguinal hernias. Due to the shared epidemiological and pathophysiological features between pelvic organ prolapse (POP) and inguinal hernias, the authors ...
N. Haya   +5 more
doaj   +1 more source

Tryptophan residue of plasmid-encoded Pgp3 is important for Chlamydia muridarum to induce hydrosalpinx in mice

open access: yesFrontiers in Microbiology, 2023
The crucial role of plasmid-encoded protein Pgp3 in Chlamydia pathogenesis has been demonstrated in various animal models. Previous studies have revealed that the Pgp3-deficient C.
Yumeng Huang   +3 more
doaj   +1 more source

Pyruvic Acid Production from Sucrose by Escherichia coli Pyruvate Dehydrogenase Variants

open access: yesFermentation, 2023
Sucrose is an abundant, cheap, and renewable carbohydrate which makes it an attractive feedstock for the biotechnological production of chemicals. Escherichia coli W, one of the few safe E.
W. Chris Moxley, Mark A. Eiteman
doaj   +1 more source

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