Results 81 to 90 of about 535,757 (290)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Critical points determination in the process of temperature sensitive products importation

, 2023
Produtos sensíveis à temperatura estão sujeitos ao Controle Sanitário cujas ações consistem na inspeção de produtos importados em portos, aeroportos e fronteiras.
Addôr, Elisabeth Claudia Lacher e
core   +1 more source

Temperature-tunable topological zero-refraction acoustic metamaterials

Frontiers in Materials
Zero-refractive index metamaterials have a wide range of applications in directional transmission and wave-front shaping due to their unusual acoustic properties.
Yangyang Chu, Tong Sun, Zhaohong Wang, Zhifeng Zhang   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Bathymetry Points, Lake Victoria, vector points, 1900 - 2017, V7

Bathymetry Points, Lake Victoria, vector point, 1900-2017 Reference Information and Units: Projected Coordinate System: Africa Lambert Conformal Conic ESRI:102024 (https://epsg.io/102024) GCS: GCS_WGS_1984 File Naming ...
Hamilton, Stuart, Kayanda, Robert, Krach, Noah, Ongore, Collins   +3 more
core   +2 more sources

A High Temperature Environment Regulates the Olive Oil Biosynthesis Network

Plants, 2020
Climate change has been shown to have a substantial impact on agriculture and high temperatures and heat stress are known to have many negative effects on the vegetative and reproductive phases of plants.
Yael Nissim, Maya Shlosberg, Iris Biton, Yair Many, Adi Doron-Faigenboim, Ran Hovav, Zohar Kerem, Benjamin Avidan, Giora Ben-Ari   +8 more
doaj   +1 more source

Temperature sensitive point mutations in fission yeast tropomyosin have long range effects on the stability and function of the actin-tropomyosin copolymer

Biochemical and Biophysical Research Communications, 2018
The actin cytoskeleton is modulated by regulatory actin-binding proteins which fine-tune the dynamic properties of the actin polymer to regulate function. One such actin-binding protein is tropomyosin (Tpm), a highly-conserved alpha-helical dimer which stabilises actin and regulates interactions with other proteins. Temperature sensitive mutants of Tpm
Chloe A. Johnson, Holly R. Brooker, Irene Gyamfi, Jennifer O'Brien, Brogan Ashley, Jodie E. Brazier, Annette Dean, James Embling, Elisabeth Grimsey, Alice C. Tomlinson, Elliot G. Wilson, Michael A. Geeves, Daniel P. Mulvihill   +12 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Determination of Deep Temperature of Acupoint, Non-acupoint on Meridian and Contral Point of Rabbit

针刺研究, 1995
Temperature is an important index to reflect the level of energy metabolism, and the temperature of the deeper tissue, relatively speaking, is stabler than the skin temperature.
王华, 刘又香, 章汉平, 邱茂良, 孙国杰   +4 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source