Results 121 to 130 of about 1,217,593 (303)

Research on optimization of temperature sensitive points of machine tool thermal error based on independent variable selection criteria

Scientific Reports
In order to improve the prediction accuracy and robustness of the machine tool thermal error model, a method to select temperature sensitive points of the machine tool thermal error model based on independent variable selection criteria is proposed.
Huadong Li, Jingjun Liu, Yang Li
openaire   +3 more sources

A Comparison of Sensitivity Metrics for Two-Stage Ignition Behavior in Rapid Compression Machines [PDF]

, 2017
A rapid compression machine (RCM) multi-zone model is used to simulate the ignition of primary reference fuel (PRF) mixtures that exhibit two-stage ignition behavior.
Allen, Casey, Wilson, David
core   +1 more source

Ultrastable lasers based on vibration insensitive cavities

, 2009
We present two ultra-stable lasers based on two vibration insensitive cavity designs, one with vertical optical axis geometry, the other horizontal. Ultra-stable cavities are constructed with fused silica mirror substrates, shown to decrease the thermal ...
C. Mandache, D. V. Magalhães, E. M. L. English, G. Santarelli, J. Lodewyck, J. Millo, P. G. Westergaard, P. Lemonde, S. Bize, S. D. Poisson, Y. Le Coq   +10 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Effects of Different Winter Wheat (Triticum aestivum L.) Varieties Addressing the Agriculture Climate Interactions in Temperature Regions of Yield

Atmosphere
Agricultural productions are deeply affected by the phenological changes, especially in Shanxi Province, where Southern Shanxi is the main production area of winter wheat.
Feng Yu, Hafeez Noor, Mahmoud F. Seleiman, Fida Noor   +3 more
doaj   +1 more source

Reliability Analysis of Temperature Influence on Stresses in Rigid Pavement Made from Recycled Materials

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016
Complex statistical and sensitivity analysis of principal stresses in concrete slabs of the real type of rigid pavement made from recycled materials is performed.
Aleš Florian, Lenka Ševelová, Jaroslav Žák   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Thermal error modeling of servo axis based on optimized LSSVM with gray wolf optimizer algorithm

Case Studies in Thermal Engineering
Thermal error of a CNC machine tool has a serious effect on its machining accuracy. In order to reduce the thermal error, establishing an accurate and robust thermal error model is necessary.
Yang Li, Yue Yang, Jiaqi Wang, Fusheng Liang   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source